Results 151 to 160 of about 447,766 (259)

Belgium [PDF]

open access: yesIMF Staff Country Reports, 2019
openaire   +1 more source

Gut–Brain Axis Modulation by Short‐Chain Fatty Acids Exerts Disease‐Modifying Effects in a Murine Model of Drug‐Resistant Epilepsy

open access: yesAnnals of Neurology, EarlyView.
Objective Drug‐resistant epilepsy (DRE) remains a clinical challenge, as therapies modifying disease trajectory are lacking. Increasing evidence implicates gut microbiota dysbiosis in epilepsy pathophysiology, with short‐chain fatty acids (SCFAs) emerging as key microbial metabolites with neuroprotective and anti‐inflammatory properties.
Akash A. Bera   +16 more
wiley   +1 more source

Solvent Hydrogen Bonding Determines Adsorption Geometry of Trimesic Acid on Cu

open access: yesAngewandte Chemie, EarlyView.
Water reorients adsorbate molecules. Combined tip‐enhanced Raman spectroscopy, density functional theory and molecular dynamics simulations reveal the adsorption geometry of trimesic acid on Cu. Subtle adsorbate–substrate–solvent energy differences due to hydrogen bonding dictate molecular orientation at solid/liquid and solid/gas interfaces, providing
Anusha Lalitha   +4 more
wiley   +2 more sources

Carbohydrate Physicochemical Properties: The Innate Hydrogen Bond Donating Capacities of α‐Glucoside and α‐Galactoside Alcohol Groups

open access: yesAngewandte Chemie, EarlyView.
Experimental determination of the innate hydrogen bond donating capacities of the glucose and galactose non‐anomeric alcohols revealed significant variations depending on position and relative configuration, which were quantified on the pKAHY scale, relevant for MedChem purposes, hence providing another tool toward rational glycomimetic development ...
Mrinal Naskar   +8 more
wiley   +2 more sources

Electrochemical Switch‐On of Nonlinear Optical Response in a Nitro‐Functionalized Arylimido‐Polyoxometalate

open access: yesAngewandte Chemie, EarlyView.
Reducing a nitro‐derivatized arylimido‐polyoxometalate (POM) reversibly switches on its second‐order NLO response, contrasting with prior donor‐functionalized systems that switch off upon reduction. Attenuation of charge‐transfer (CT) to the POM upon reduction gives a more strongly dipolar imido/π‐bridge to ─NO2 CT, signal enhancement of up to 15× (β ...
Claire F. Jones   +7 more
wiley   +2 more sources

Tailoring Photochromism Beyond Human Eye Visibility: On/Off Switchable NIR Absorption in an Aluminosilicate

open access: yesAngewandte Chemie, EarlyView.
A new photochromic material was developed. Its on/off‐switchable absorption band is situated completely outside the human eye's visibility, in the near‐infrared (NIR) region, a feature never reported before. The photochromism mechanism in this aluminosilicate is elucidated by combining experimental as well as computational results, and the material's ...
Bettiina Muurinen   +15 more
wiley   +2 more sources

Von In‐Silico bis In‐Cerebro – Entwicklung des Orexinrezeptor Antagonisten „Photorexant“ zur Photomodulation In Vitro und im Gehirn der Maus

open access: yesAngewandte Chemie, EarlyView.
Durch einen strukturbasierten Designansatz wurden photoschaltbare Derivate des von der FDA zugelassenen Arzneistoffes Suvorexant entwickelt, gedockt, synthetisiert und pharmakologisch an den Orexin‐1‐ und 2‐Rezeptoren (OX1R und OX2R) charakterisiert.
Marcus Angermann   +10 more
wiley   +1 more source

Correction: A Randomized clinical trial evaluating the impact on survival and quality of life of 177Lutetium[Lu]-edotreotide versus everolimus in patients with neuroendocrine tumors of the lung and thymus: the LEVEL study (GETNE T-2217). [PDF]

open access: yesBMC Cancer
Capdevila J   +34 more
europepmc   +1 more source

Correction: Multianalyte nano-biosensor diagnostics: advances through microfluidic and AI integration. [PDF]

open access: yesFront Bioeng Biotechnol
Pathak S   +4 more
europepmc   +1 more source

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