Results 151 to 160 of about 447,766 (259)
Objective Drug‐resistant epilepsy (DRE) remains a clinical challenge, as therapies modifying disease trajectory are lacking. Increasing evidence implicates gut microbiota dysbiosis in epilepsy pathophysiology, with short‐chain fatty acids (SCFAs) emerging as key microbial metabolites with neuroprotective and anti‐inflammatory properties.
Akash A. Bera +16 more
wiley +1 more source
Solvent Hydrogen Bonding Determines Adsorption Geometry of Trimesic Acid on Cu
Water reorients adsorbate molecules. Combined tip‐enhanced Raman spectroscopy, density functional theory and molecular dynamics simulations reveal the adsorption geometry of trimesic acid on Cu. Subtle adsorbate–substrate–solvent energy differences due to hydrogen bonding dictate molecular orientation at solid/liquid and solid/gas interfaces, providing
Anusha Lalitha +4 more
wiley +2 more sources
Experimental determination of the innate hydrogen bond donating capacities of the glucose and galactose non‐anomeric alcohols revealed significant variations depending on position and relative configuration, which were quantified on the pKAHY scale, relevant for MedChem purposes, hence providing another tool toward rational glycomimetic development ...
Mrinal Naskar +8 more
wiley +2 more sources
Reducing a nitro‐derivatized arylimido‐polyoxometalate (POM) reversibly switches on its second‐order NLO response, contrasting with prior donor‐functionalized systems that switch off upon reduction. Attenuation of charge‐transfer (CT) to the POM upon reduction gives a more strongly dipolar imido/π‐bridge to ─NO2 CT, signal enhancement of up to 15× (β ...
Claire F. Jones +7 more
wiley +2 more sources
Beyond routine bronchoscopy during percutaneous dilatational tracheostomy: should systematic ultrasonography be considered? [PDF]
Honoré PM +4 more
europepmc +1 more source
A new photochromic material was developed. Its on/off‐switchable absorption band is situated completely outside the human eye's visibility, in the near‐infrared (NIR) region, a feature never reported before. The photochromism mechanism in this aluminosilicate is elucidated by combining experimental as well as computational results, and the material's ...
Bettiina Muurinen +15 more
wiley +2 more sources
Durch einen strukturbasierten Designansatz wurden photoschaltbare Derivate des von der FDA zugelassenen Arzneistoffes Suvorexant entwickelt, gedockt, synthetisiert und pharmakologisch an den Orexin‐1‐ und 2‐Rezeptoren (OX1R und OX2R) charakterisiert.
Marcus Angermann +10 more
wiley +1 more source
Correction: A Randomized clinical trial evaluating the impact on survival and quality of life of 177Lutetium[Lu]-edotreotide versus everolimus in patients with neuroendocrine tumors of the lung and thymus: the LEVEL study (GETNE T-2217). [PDF]
Capdevila J +34 more
europepmc +1 more source
Correction: Multianalyte nano-biosensor diagnostics: advances through microfluidic and AI integration. [PDF]
Pathak S +4 more
europepmc +1 more source

