Results 81 to 90 of about 760,634 (252)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Kur’an’ın Işığında Kader Konusuna Bakış

Umde Dini Tetkikler Dergisi, 2018
Kader konusu çok eski zamanlardan beri üzerinde tartışılan konulardan biridir. İlâhî dinler ve düşünce âlemi de dâhil olmak üzere, insanlık âlemi kader konusunda ikiye bölünmüştür; kaderi kabul edenler ve inkâr edenler. Bu araştırmada kader inancının Kur’
Abdullah Namlı
doaj  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Marcus on Belief and Belief in the Impossible [PDF]

, 2013
I review but don’t endorse Marcus’ arguments that impossible beliefs are impossible. I defend her claim that belief’s objects are, in some important sense, not the bearers of truth and falsity, discuss her dispositionalism about belief, and argue it’s a ...
Richard, Mark, Mark Richard
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Policy shaping based on the learned preferences of others accounts for risky decision-making under social observation

eLife
Observing others’ choices influences individuals’ decisions, often leading them to follow others. However, it is repeatedly reported that being observed by others tends to make people act more riskily.
HeeYoung Seon, Dongil Chung
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

KUR'AN IŞIGINDA DÜŞÜNCE, iNANÇ VE iFADE HÜRRiYETi

Fırat Üniversitesi İlahiyat Fakültesi Dergisi, 2005
According to the Qur'an no one has the right to oppress or interfere wıtlı anya ne 's fa ith or beliejs. Human beings are completely free to believe or not to believe anything they choose wlıetlıer they practice or not wlıat they believe in.
Abdulbaki Güneş
doaj  

Third-hand Smoking Beliefs in Patients with Cancer

Thoracic Research and Practice
OBJECTIVE: Exposure to third-hand smoke (THS) represents an important health concern in many indoor environments. This study was conducted to test the beliefs of cancer patients about THS and to examine associations with effective factors.
Remziye Can, Elif Saraç, Esra Yıldız, Şerif Kurtuluş   +3 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source