Results 91 to 100 of about 1,243,465 (283)

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Harmonization of the Activity of the Left and Right Cerebral Hemispheres - an Important Component of the Spiritual and Mental Health of Individual and Humanity

Mental Health, 2020
Introduction According to modern scholars (N. Maslova, B. Astafiev), one of the important reasons for the global planetary crisis, including modern educational system in particular, is violation of the conformity of nature principles in the process of ...
Tamara Tyurina, Sofiya Stavkova
doaj   +1 more source

Aqueous Two‐Phase Bioinks for Discrete Packing and Compartmentalization of 3D Bioprinted Cells

Advanced Healthcare Materials, EarlyView.
Aqueous two‐phase systems (ATPS) enable the formation of biomimetic interfaces crucial for tissue engineering. However, clinical translation remains limited by the challenge of precisely controlling cellular compartmentalization. Here, we developed ATPS biomaterial inks for 3D bioprinting allowing tuneable droplet formation via NaCl modulation.
Martina Marcotulli, Arianna Iacomino, Federico Serpe, Lucia Iafrate, Marco Bastioli, Giorgia Montalbano, Michele D'Orazio, Biagio Palmisano, Silvia Franco, Arianna Mencattini, Roberta Angelini, Eugenio Martinelli, Alessandro Corsi, Mara Riminucci, Giancarlo Ruocco, Chiara Scognamiglio, Andrea Barbetta, Gianluca Cidonio   +17 more
wiley   +1 more source

A Framework for Probabilistic Multi-Hazard Assessment of Rain-Triggered Lahars Using Bayesian Belief Networks

Frontiers in Earth Science, 2017
Volcanic water-sediment flows, commonly known as lahars, can often pose a higher threat to population and infrastructure than primary volcanic hazardous processes such as tephra fallout and Pyroclastic Density Currents (PDCs).
Pablo Tierz, Mark J. Woodhouse, Jeremy C. Phillips, Laura Sandri, Jacopo Selva, Warner Marzocchi, Henry M. Odbert, Henry M. Odbert   +7 more
doaj   +1 more source

Fluid Forces Control Structural Remodeling of Blind‐Ended Lymphatic Microvessels

Advanced Healthcare Materials, EarlyView.
Using innovative microfluidic biofabrication with fluid mechanical insights, we recapitulated the blind‐ended microanatomy and physiological drainage properties of capillary lymphatics. Our results reveal the interrelationship between intra‐ and extraluminal regions of lymphatic vessels due to flow‐induced sprouting and morphological changes that ...
Jacob C. Holter, Shashwat S. Agarwal, Joseph W. Tinapple, Joseph M. Barlage, Travis H. Jones, Jonathan W. Song   +5 more
wiley   +1 more source

Ilustración y liberalismo en la obra de Juan Sempere y Guarinos (1754-1830)

Studia Historica: Historia Moderna, 2009
RESUMEN: Juan Sempere y Guarinos fue un miembro notable del elenco ilustrado español. Su ideario es el resultado de la confluencia de diversas corrientes modernizadoras: el humanismo y el arbitrismo españoles, la Ilustración italiana, la Ilustración ...
Juan RICO GIMÉNEZ
doaj   +2 more sources

Clustering by soft-constraint affinity propagation: Applications to gene-expression data

, 2007
Motivation: Similarity-measure based clustering is a crucial problem appearing throughout scientific data analysis. Recently, a powerful new algorithm called Affinity Propagation (AP) based on message-passing techniques was proposed by Frey and Dueck ...
Alizadeh, Blatt, Braunstein, Golub, M. Leone, M. Weigt, Pomeroy, Sumedha,   +7 more
core   +4 more sources

On the Merit of Selecting Different Belief Merging Operators [PDF]

, 2013
Belief merging operators combine multiple belief bases (a profile) into a collective one. When the conjunction of belief bases is consistent, all the operators agree on the result. However, if the conjunction of belief bases is inconsistent, the results vary between operators.
Pozos-Parra, Pilar, McAreavey, Kevin, Liu, Weiru   +2 more
openaire   +2 more sources

Copper–Collagen Interactions Regulate the Mechanical and Invasive Properties of Tumor Spheroids

Advanced Healthcare Materials, EarlyView.
Ionic copper is investigated as a modulator of tumor spheroid growth and invasiveness in a 3D microfluidic glioblastoma model. Copper exposure alters metabolic activity, cytoskeletal organization, protrusion dynamics, and EMT‐related phenotypes in a dose‐ and timing‐dependent manner, revealing how copper bioavailability shapes tumor aggressiveness ...
Paula Guerrero‐López, Jose I. Garcia‐Peiro, Felipe Hornos, Jose L. Hueso, Jesus Santamaria, J. Manuel Garcia‐Aznar   +5 more
wiley   +1 more source

Nanobody‐Conjugated Theranostic Prodrug Targeting αvβ3 Integrin Enables Precision Cancer Therapy With Real‐Time Imaging

Advanced Healthcare Materials, EarlyView.
The image shows a schematic form a nanobody‐conjugated theranostic prodrug (NBD) platform targeting tumor‐associated αvβ3 integrin. The NBD system integrates selective nanobody‐mediated tumor recognition, glutathione‐responsive disulfide cleavage for doxorubicin release, and aza‐BODIPY‐based near‐infrared fluorescence for real‐time imaging.
Sanu Karan, Hyunseung Lee, Rema Naskar, Mi Young Cho, Hye Sun Park, Eun Hee Han, Soumyadip Hore, Sun Hee Cho, Truc Ngoc Kim Lam, Taewoong Son, Tae Jung Park, Inkyu Hwang, Jonathan L. Sessler, Kwan Soo Hong   +13 more
wiley   +1 more source