Results 41 to 50 of about 160,175 (304)

Exploiting degeneracy in belief propagation decoding of quantum codes

open access: yesnpj Quantum Information, 2022
Quantum information needs to be protected by quantum error-correcting codes due to imperfect physical devices and operations. One would like to have an efficient and high-performance decoding procedure for the class of quantum stabilizer codes.
Kao-Yueh Kuo, Ching-Yi Lai
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

A Homological Approach to Belief Propagation and Bethe Approximations

open access: yes, 2019
We introduce a differential complex of local observables given a decomposition of a global set of random variables into subsets. Its boundary operator allows us to define a transport equation equivalent to Belief Propagation.
AG Schlijper   +11 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Belief Propagation, Bethe Approximation and Polynomials

open access: yes, 2017
Factor graphs are important models for succinctly representing probability distributions in machine learning, coding theory, and statistical physics. Several computational problems, such as computing marginals and partition functions, arise naturally ...
Straszak, Damian, Vishnoi, Nisheeth K.
core   +1 more source

Approaching the Rate-Distortion Limit with Spatial Coupling, Belief propagation and Decimation [PDF]

open access: yes, 2015
We investigate an encoding scheme for lossy compression of a binary symmetric source based on simple spatially coupled Low-Density Generator-Matrix codes.
Aref, Vahid   +2 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Propagating Beliefs in Spin-Glass Models [PDF]

open access: yesJournal of the Physical Society of Japan, 2003
We investigate dynamics of an inference algorithm termed the belief propagation (BP) when employed in spin glass (SG) models and show that its macroscopic behaviors can be traced by recursive updates of certain auxiliary field distributions whose stationary state reproduces the replica symmetric solution offered by the equilibrium analysis.
openaire   +3 more sources

The condensation phase transition in the regular $k$-SAT model [PDF]

open access: yes, 2015
Much of the recent work on random constraint satisfaction problems has been inspired by ingenious but non-rigorous approaches from physics. The physics predictions typically come in the form of distributional fixed point problems that are intended to ...
Bapst, Victor, Coja-Oghlan, Amin
core   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

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