Results 141 to 150 of about 3,358,093 (408)
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Epistemological Beliefs and Self-directed Learning Readiness of Hospitality Students: The Necessary Precursor to Academic Performance [PDF]
Throughout the philosophical literature, studies on epistemological beliefs have been well documented. However, within the educational context, this philosophical construct is a recent phenomenon.
Rahmat Hashim +3 more
doaj
Guddiri People’s Belief System in The Unusual Functions of Apple-Ring Tree (Faidherbia Albida) As A Measure of Their Scientific Literacy [PDF]
Mohammed Yunusa +2 more
openalex +1 more source
A simple modal logic for belief revision [PDF]
We propose a modal logic based on three operators, representing intial beliefs, information and revised beliefs. Three simple axioms are used to provide a sound and complete axiomatization of the qualitative part of Bayes’ rule.
Giacomo Bonanno
core
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Erratum: Perception, beliefs, and causal attribution of autism early signs in Ecuadorian general population [PDF]
Frontiers Production Office
openalex +1 more source
Towards an ontology of common sense [PDF]
Philosophers from Plotinus to Paul Churchland have yielded to the temptation to embrace doctrines which contradict the core beliefs of common sense. Philosophical realists have on the other hand sought to counter this temptation and to vindicate those ...
Smith, Barry
core
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Improved belief propagation decoding algorithm based on decoupling representation of Pauli operators for quantum LDPC codes [PDF]
Zhengzhong Yi +5 more
openalex +1 more source
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source

