Results 81 to 90 of about 571,567 (314)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

ANALYSIS OF THE EFFICIENCY OF RED CERAMIC COMPANIES IN THE REGION OF CARAJÁS-PA

open access: yesRevista Produção e Desenvolvimento, 2018
The purpose of this paper is to analyze the efficiency of companies in the ceramic sector located in the region of Carajás / PA, based on Data Envelopment Analysis (DEA), using as information base data collected from 21 local companies.
Fayla Fabiana Soares dos Santos   +3 more
doaj   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

EUPP-benchmark/ESSD-mbm: version 1.0 release

open access: yes, 2023
Member-By-Member (MBM) scripts for the ESSD benchmark. Provide the MBM output file. This code is provided as supplementary material with: Demaeyer, J., Bhend, J., Lerch, S., Primo, C., Van Schaeybroeck, B., Atencia, A., Ben Bouallègue, Z., Chen, J ...
Demaeyer, Jonathan
core   +1 more source

Evaluation of a Novel Electric Health Record Sidecar Application to Display Rheumatoid Arthritis Clinical Outcomes During Clinic Visits: Results of a Stepped‐Wedge Cluster Randomized Pragmatic Trial

open access: yesArthritis Care &Research, EarlyView.
Objective We developed a novel electronic health record sidecar application to visualize key rheumatoid arthritis (RA) outcomes, including disease activity, physical function, and pain, via a patient‐facing graphical interface designed for use during outpatient visits (“RA PRO dashboard”).
Gabriela Schmajuk   +16 more
wiley   +1 more source

RockCloud-Align: A High-Precision Benchmark for Rock-Mass Point-Cloud Registration

open access: yesRemote Sensing
Rock-mass point-cloud registration is a critical yet challenging task in the fields of geology and engineering. Currently, the lack of dedicated datasets for rock-mass point-cloud registration significantly limits the development and application of ...
Yunbiao Wang   +3 more
doaj   +1 more source

Benchmarking the Benchmarks

open access: yesProceedings of the ACM Asia Conference on Computer and Communications Security, 2023
Marc Miltenberger   +3 more
openaire   +1 more source

Benchmarking for Steganography [PDF]

open access: yes, 2008
With the increasing number of new steganographic algorithms as well as methods for detecting them, the issue of comparing security of steganographic schemes in a fair manner is of the most importance. A fair benchmark for steganography should only be dependent on the model chosen to represent cover and stego objects.
Tomás Pevný, Jessica J. Fridrich
openaire   +1 more source

Prevalence of Systemic Lupus Erythematosus in Australia, 2010–2022: A Population‐Based Study Using Linked National Administrative Health Data

open access: yesArthritis Care &Research, EarlyView.
Objective Systemic lupus erythematosus (SLE) is a heterogenous inflammatory condition with widely varying global prevalence estimates. The frequency of SLE in the general population of Australia has been reported to be notably lower than contemporary estimates in countries such as the United States or United Kingdom, at 19 to 39 per 100,000 as opposed ...
Lucinda Roper   +7 more
wiley   +1 more source

Analiza stanja pri uvajanju sodobnega višinskega sistema : Status of the new height system development [PDF]

open access: yesGeodetski Vestnik, 2011
V prispevku je predstavljen predlog za novo oštevilčevanje nivelmanskih poligonov in reperjev. Obravnavana je tudi analiza natančnosti izmerjenih višinskih razlik, opravljena na podlagi odstopanj obojestransko merjenih višinskih razlik in odstopanj pri ...
Božo Koler   +2 more
doaj  

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