Results 41 to 50 of about 96,235 (264)
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Benchmarking offshore drilling: methodology and case study [PDF]
REM: International Engineering JournalOil exploration is complex and very expensive, presenting long-term returns and considerable risks of accidents. Saving time is the guideline of any optimization method to reduce drilling costs and CO2 emissions. Highly variable performances are found in
Dalmo S. Amorim Jr. +3 more
doaj +1 more source
Benchmarking for Steganography [PDF]
, 2008 With the increasing number of new steganographic algorithms as well as methods for detecting them, the issue of comparing security of steganographic schemes in a fair manner is of the most importance. A fair benchmark for steganography should only be dependent on the model chosen to represent cover and stego objects.
Tomás Pevný, Jessica J. Fridrich
openaire +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
REGULATORY BENCHMARKING IN CENTRAL EUROPE: CURRENT PRACTICE AND POSSIBILITIES OF DEVELOPMENT FOR THE ENERGY SECTOR [PDF]
Annals of the University of Oradea: Economic Science, 2011 Benchmarking is a technique of performance evaluation in which comparisons are made to benchmarks that represent external performance standards. In the field of regulation of public utilities, benchmarking can be used as an element of performance-based ...
Machek Ondrej
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang +8 more
wiley +1 more source
Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig +9 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Investment Policy in the Conditions of the Knowledge Economy: New Tools and Valuable Bases
Управленческое консультирование, 2018 The article is devoted to research of specific goals, objectives and content of the state investment policy in the conditions of formation and development of the knowledge-based economy.
A. V. Kurochkin, I. A. Babyuk
doaj +1 more source