Results 71 to 80 of about 185,092 (310)
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Benchmarking logistischer Dienstleistungsprozesse
S.105-122Benchmarking als die Suche nach besten Praktiken, die zu Spitzenleistungen führen, ist laut einer aktuellen Studie von Bain & Company eines der weltweit am meisten genutzten Managementinstrumente.
Jehle, Franziska +3 more
core +1 more source
Objective We developed a novel electronic health record sidecar application to visualize key rheumatoid arthritis (RA) outcomes, including disease activity, physical function, and pain, via a patient‐facing graphical interface designed for use during outpatient visits (“RA PRO dashboard”).
Gabriela Schmajuk +16 more
wiley +1 more source
BENCHMARKING - A VALID STRATEGY FOR THE LONG TERM? [PDF]
The present paper work deals with a popular method for developingrequirements and setting goals ââ¬â benchmarking. It contains general aspects about thispowerful performance improvement tool, including types of benchmarking, steps tofollow in ...
Larisa Dragolea, Denisa Cotirlea
core
Factory Flow Benchmarking Report [PDF]
LAI benchmarked representative part fabrications and some assembly operations within its member companies of the defense aircraft industry. This paper reports the results of this benchmarking effort. In addition, this report explores the major components
Shields, Thomas J.
core
»Steigerung der Wettbewerbsfähigkeit privater und öffentlicher Unternehmen« ist das Motto der fünften Benchmarking-Tagung, die in Verbindung mit dem 3.
Kohl, H., Mertins, K.
core
Objective Systemic lupus erythematosus (SLE) is a heterogenous inflammatory condition with widely varying global prevalence estimates. The frequency of SLE in the general population of Australia has been reported to be notably lower than contemporary estimates in countries such as the United States or United Kingdom, at 19 to 39 per 100,000 as opposed ...
Lucinda Roper +7 more
wiley +1 more source
BENCHMARKING FINANCIAL PERFORMANCE: A COMPARATIVE APPROACH [PDF]
The concept of benchmarking comes from English, it is also known as comparative performance analysis and represents a strategic and operational management method adopted by companies with the aim of improving performance.
ECOBICI MIHAELA LOREDANA
doaj
Marc Miltenberger +3 more
openaire +1 more source

