Results 221 to 230 of about 596,491 (297)

Exploring the effects and potential of unlocked I/O-powered single board computer clusters. [PDF]

Sci Rep
Lee Y, Park D.
europepmc   +1 more source

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

Volumetric additive manufacturing of complex geometries around complex inserts. [PDF]

Sci Rep
Bagheri A, Zakerzadeh MR, Sadigh MJ, Salehabadi R.   +3 more
europepmc   +1 more source

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

Advanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum, Leo A. H. Zeef, Lee A. Stevens, Marco A. N. Domingos, Susan J. Kimber, Mahetab H. Amer   +5 more
wiley   +1 more source

Building a continuous benchmarking ecosystem in bioinformatics. [PDF]

PLoS Comput Biol
Mallona I, Soneson C, Carrillo B, Lütge A, Incicau D, Gerber R, Sonrel A, Robinson MD.   +7 more
europepmc   +1 more source

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

A primer on prescription drug pricing benchmarks in the United States. [PDF]

J Manag Care Spec Pharm
Hung A, Dickson S.
europepmc   +1 more source

Development of a Synthetic Hydrogel to Foster Microvascularization of an Endometriosis Microphysiological System

Advanced Healthcare Materials, EarlyView.
ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett, Laura Bahlmann, Ryan Ogi, Angela Jiao, Priyatanu Roy, Matthew Johnson, David Trumper, Linda Griffith   +7 more
wiley   +1 more source

Accountable Care Organization Efficiency on Entry and Shared Savings Bonuses.

JAMA Netw Open
Srivastava A, Shay A, Kaufman SR, Liu X, Maganty A, Oerline MK, Guro PA, Hill D, Dall C, Faraj KS, Ying M, Shahinian VB, Hollenbeck BK.   +12 more
europepmc   +1 more source

The Journey Towards Professional Excellence: Building the Foundation and Cultivating a Culture of Excellence. [PDF]

Nurs Adm Q
Sohal J.
europepmc   +1 more source