Results 41 to 50 of about 126,370 (292)

The effects of internal erosion on granular soils used in transport embankments

open access: yesSoils and Foundations
The flooding of embankments used for rail and other infrastructure has the potential to cause lasting weakening of slopes via the movement of fine particles induced by seepage.
I. Johnston, W. Murphy, J. Holden
doaj   +1 more source

Small-strain stiffness of liquefiable sands: A comparison between bender elements and resonant-column tests [PDF]

open access: yesE3S Web of Conferences
Soil stiffness can be estimated by geophysical and dynamic testing methods. In the laboratory, the most common methods to measure the small-strain stiffness are the bender elements (BE) and resonant-column (RC) tests. This paper focuses on the comparison
Molina-Gomez Fausto   +3 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Utilização de bender elements na determinação do módulo de distorção [PDF]

open access: yes, 2013
Este trabalho apresenta a utilização de bender elements na determinação do módulo de distorção de uma areia. A amostra foi preparada para um determinado índice de vazios e ensaiada à compressão isotrópica até 400 kPa.
Araújo, Nuno Miguel Faria   +3 more
core  

Tracking degradation of argillaceous rocks using bender elements

open access: yes, 2011
The results of a comprehensive experimental program focused on the study of progressive degradation processes on a low permeability argillaceous rock induced by hydraulic cycles is presented in the paper. Relative humidity cycles were applied with vapour transfer technique, and bender elements were used to evaluate the evolution of shear stiffness ...
Pineda, Jubert Edgar   +2 more
openaire   +2 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Stress path dependent small strain stiffness of Shanghai clay [PDF]

open access: yesE3S Web of Conferences, 2019
The soil small strain stiffness plays an important role in many geotechnical applications such as machine foundations, deep excavations and earthquake ground response analysis.
Gu Xiaoqiang   +3 more
doaj   +1 more source

Pairing correlations beyond the mean field

open access: yes, 2006
We discuss dynamical pairing correlations in the context of configuration mixing of projected self-consistent mean-field states, and the origin of a divergence that might appear when such calculations are done using an energy functional in the spirit of ...
Bender M.   +4 more
core   +2 more sources

Non-Hermitian oscillators with $T_{d}$ symmetry [PDF]

open access: yes, 2014
We analyse some PT-symmetric oscillators with $T_{d}$ symmetry that depend on a potential parameter $g$. We calculate the eigenvalues and eigenfunctions for each irreducible representation and for a range of values of $g$.
Amore, Paolo   +2 more
core   +2 more sources

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