Results 31 to 40 of about 14,567 (262)

Ethical Challenges Involved in COVID-19 Vaccine Mandates for Children: A Systematic Review

open access: yesVaccines, 2023
The new COVID-19 pandemic has affected day-to-day life, creating various ethical dilemmas. COVID-19 vaccination is seen as an effective way to halt the pandemic.
Ghiath Alahmad
doaj   +1 more source

Real‐World Trends in Prenatal Antirheumatic Drug Utilization in Ontario, Canada: A Cross‐Sectional Time‐Series Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah   +6 more
wiley   +1 more source

Pharmacovigilance and bioethics: the importance of a neglected relationship

open access: yesFrontiers in Drug Safety and Regulation
This study examines the critical, yet often neglected, link between bioethics and pharmacovigilance—disciplines that collectively aim to ground drug therapies in robust evidence and respect for patient rights.
Giuseppe Alvaro   +3 more
doaj   +1 more source

Race and Household Income Are Associated With Disease Outcomes in Pediatric Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Hospitalized in the United States

open access: yesArthritis Care &Research, EarlyView.
Objective Race and household income impact outcomes in patients with rheumatic conditions; however, their role in pediatric antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) remains poorly understood. We aimed to evaluate whether race and ethnicity and household income are associated with severe AAV disease and renal outcomes among
Roberto Alejandro Valdovinos   +2 more
wiley   +1 more source

The Effect of Impartial Beneficence on Bystander Cooperation Behavior: The Roles of Social Perception and Impartial Beneficence Personality

open access: yesBehavioral Sciences
Previous research on utilitarianism has focused predominantly on instrumental harm while neglecting the investigation of impartial beneficence. This study designed three progressive experiments (total n = 1378) to explore how impartial beneficence ...
Xiaodan Xu   +5 more
doaj   +1 more source

A study of the validity and reliability of the questionnaire entitled “physicians' approach to and disclosure of medical errors and the related ethical issues”

open access: yesJournal of Medical Ethics and History of Medicine, 2019
Medical errors are among the major challenges that threaten patients’ health worldwide. The aim of this study was to design a valid and reliable questionnaire to investigate the status of medical error disclosure by physicians.
Mohammad Mohammadi   +5 more
doaj   +1 more source

Mapping the “Supply–Demand–Flow” of Ecosystem Services for Ecosystem Management in China

open access: yesAdvanced Science, EarlyView.
This study develops a “supply–demand–flow” framework clarifies how ecosystem services move between regions by distinguishing potential and actual supply and demand. Using integrated biophysical–socioeconomic modeling, nine services in China were mapped.
Yikun Zhang   +3 more
wiley   +1 more source

Do You Care for Robots That Care? Exploring the Opinions of Vocational Care Students on the Use of Healthcare Robots

open access: yesRobotics, 2019
Background: There has been a rapid increase in the population of senior citizens in many countries. The shortage of caregivers is becoming a pressing concern. Robots are being deployed in an attempt to fill this gap and reduce the workload of caregivers.
Margo A. M. van Kemenade   +2 more
doaj   +1 more source

On the beneficent thickness of water [PDF]

open access: yesInterface Focus, 2019
In the 1930s, Lars Onsager published his famous ‘reciprocal relations’ describing free energy conversion processes. Importantly, these relations were derived on the assumption that the fluxes of the processes involved in the conversion were proportional to the forces (free energy gradients) driving them.
E. Branscomb, M. J. Russell
openaire   +2 more sources

Heat Shock Protein 90: From Molecular Chaperone Function to Therapeutic Targeting in Malignancies

open access: yesAdvanced Science, EarlyView.
In this review, an integrated conceptual framework linking HSP90's molecular chaperone functions to its pathological roles in cancer is proposed. HSP90 serves as a central node that integrates oncogenic signaling, buffers proteotoxic stress, maintains cancer stem cell plasticity, and shapes tumor‐immune interactions, all of which converge to drive ...
Beibei Zhang   +4 more
wiley   +1 more source

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