Results 101 to 110 of about 6,775,448 (288)

An interdisciplinary model for mapping the Normative diffusion of fair and equitable benefit-sharing [PDF]

, 2015
Fair and equitable benefit-sharing is emerging in various areas of international environmental law (biodiversity, oceans, climate change, water, food and agriculture), as well as in international processes on human rights and corporate accountability ...
Morgera, Elisa, Parks, Louisa
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

The evolution of cooperation by social exclusion [PDF]

, 2012
The exclusion of freeriders from common privileges or public acceptance is widely found in the real world. Current models on the evolution of cooperation with incentives mostly assume peer sanctioning, whereby a punisher imposes penalties on freeriders ...
Sasaki, Tatsuya, Uchida, Satoshi
core   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Biopiracy versus one-world medicine – from colonial relicts to global collaborative concepts [PDF]

, 2019
Background: Practices of biopiracy to use genetic resources and indigenous knowledge by Western companies without benefit-sharing of those, who generated the traditional knowledge, can be understood as form of neocolonialism.Hypothesis: : The One-World ...
Abdelfatah, Sara, Abu-Darwish, Mohammad Sanad, Banerjee, Mita, Bhakta-Guha, Dipita, Bockers, Madeleine, Bolzani, Vanderlan, Daak, Salah, Dawood, Mona, Demirezer, Omur Lutfiye, Efferth, Monika, Efferth, Thomas, El-Seedi, Hesham R., Fischer, Nicolas, Greten, Henry J., Hamdoun, Sami, Hong, Chunlan, Horneber, Markus, Kadioglu, Onat, Khalid, Hassan E., Khalid, Sami A., Kuete, Victor, Mahmoud, Nuha, Marin, José, Mbaveng, Armelle, Midiwo, Jacob, Nakagawa, Hiroshi, Naß, Janine, Ngassapa, Olipa, Ochwang, Dominic, Omosa, Leonida K., Ooko, Edna A., Paramasivan, Poornima, Paul, Norbert W., Rodriguez Romero, Marta, Saeed, Elfatih M., Saeed, Mohamed E.M., Salgueiro, Ligia, Seo, Ean-Jeong, Yan, Ge, Yasin, Zahir, Özenver, Nadire   +40 more
core   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Property rights and benefit sharing: a case study of the Barotse floodplain of Zambia

International Journal of the Commons, 2016
The study sought to expose the underlying complexity of benefit sharing of ecosystem goods and services among multiple actors in the Barotse Floodplains of Zambia.
Machaya Jeff Chomba, Bimo Abraham Nkhata
doaj   +1 more source

Narratives in REDD+ benefit sharing: examining evidence within and beyond the forest sector

Climate Policy, 2019
REDD+ was designed globally as a results-based instrument to incentivize emissions reduction from deforestation and forest degradation. Over 50 countries have developed strategies for REDD+, implemented pilot activities and/or set up forest monitoring ...
G. Wong, C. Luttrell, L. Loft, A. Yang, T. T. Pham, D. Naito, S. Assembe-Mvondo, M. Brockhaus   +7 more
semanticscholar   +1 more source

Benefit Sharing for Solving Transboundary Commons Dilemma in Central Asia

International Journal of the Commons, 2020
Transboundary water governance often represents challenges specific to the commons dilemma. Use of water in one country affects use in another country, yet dynamic and diverse political and socioeconomic factors coupled with relatively large size of a ...
Ilkhom Soliev, I. Theesfeld
semanticscholar   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source