Results 111 to 120 of about 6,775,448 (288)
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Project A1a: On designing and implementing benefit-sharing mechanisms : [PDF]
, 2011 This is about identifying which benefit-sharing and coordination mechanisms work best under which circumstances for basins anywhere in the Andes and the reasons underpinning failure or success in specific basin instances.
Mulligan, Mark +1 more
core
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Who Should Benefit from REDD+? Rationales and Realities
Ecology and Society, 2013 Benefit-sharing mechanisms are a central design aspect of REDD+ because they help to create the necessary incentives to reduce carbon emissions. However, if stakeholders do not perceive the benefit sharing as fair, the legitimacy of REDD+, and support ...
Cecilia Luttrell +6 more
doaj +1 more source
REDD-based Offsets: Benefit Sharing and Risks [PDF]
, 2015 In this study we apply systems analysis methods to modeling financial instruments supporting the Reduced Emissions from Deforestation and Degradation (REDD) program.
Khabarov, N. +2 more
core
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Environmental & Socio-economic Studies, 2020 Mining is essentially an important income generating activity in the developing countries of the world. This is beneficial for their social and economic development and thus developing countries place a great dependence on their exploitation of mineral ...
Nath Swami, Singh Ranveer
doaj +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Learning from farmer-led access and benefit sharing. Conclusions. [PDF]
, 2016 This special issue of Farming Matters magazine has explored the ways in which access and benefit sharing of plant genetic resources can work for family farmers.
Bruil, J. +2 more
core
a community forest case-study in Tanzania [PDF]
, 2010 The current debate on climate change, especially with respect to the role of REDD projects and the push for the recognition of community (participatory) forest management as a carbon mitigation option represents a potential for communities to receive ...
Re, Riccardo da +2 more
core +1 more source