Results 81 to 90 of about 1,862,201 (299)

A Reputation Economy: Results from an Empirical Survey on Academic Data Sharing [PDF]

open access: yes, 2015
Academic data sharing is a way for researchers to collaborate and thereby meet the needs of an increasingly complex research landscape. It enables researchers to verify results and to pursuit new research questions with "old" data.
Fecher, Benedikt   +4 more
core   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Exploring manuscripts: sharing ancient wisdoms across the semantic web [PDF]

open access: yes, 2012
Recent work in digital humanities has seen researchers in-creasingly producing online editions of texts and manuscripts, particularly in adoption of the TEI XML format for online publishing.
Hedges, Mark   +3 more
core   +1 more source

Population Genetics and Benefit Sharing

open access: yesPublic Health Genomics, 2000
The majority of international or national guidelines, specific to human genetics concentrate on actual or potential clinical applications. In contrast, the Ethics Committee of the Human Genome Organisation (HUGO) attempts to provide guidance to the bench scientists engaged in fundamental research in genomics prior to any clinical applications.
openaire   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Bridging the Nagoya Compliance Gap: The Fundamental Role of Customary Law in Protection of Indigenous Peoples’ Resource and Knowledge Rights [PDF]

open access: yesLaw, Environment and Development Journal, 2013
The Nagoya Protocol requires states to ensure that access to and use of genetic resources and traditional knowledge of Indigenous peoples and local communities is subject to their prior informed consent (PIC).
Brendan M. Tobin
doaj  

Reform and Improvement of Legal Regulation of Marine Biodiversity Beyond National Jurisdiction: Comment on 'BBNJ Agreement (Draft) '

open access: yesHaiyang Kaifa yu guanli, 2023
The "BBNJ Agreement" has created a benefit-sharing system for marine genetic resources and changed the existing legislation on the "first-come, first-served" commercial utilization rules for the resources; It also has established a global mechanism for ...
Shanbao ZHANG
doaj  

Analysis of Solar Energy Aggregation under Various Billing Mechanisms

open access: yes, 2018
Ongoing reductions in the cost of solar photovoltaic (PV) systems are driving their increased installations by residential households. Various incentive programs such as feed-in tariff, net metering, net purchase and sale that allow the prosumers to sell
Baeyens, Enrique   +4 more
core   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Prospects and Challenges for Harnessing Opportunities in Medicinal Plants Sector in India [PDF]

open access: yesLaw, Environment and Development Journal, 2006
The importance of the medicinal plants sector can be gauged from the fact that herbal medicines serve the healthcare needs of about 80 per cent of the world's population.
Harbir Singh
doaj  

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