Results 81 to 90 of about 2,952,520 (287)

Planning on law: Fair and just in the division of benefits. The case of genetic resources in the high seas (water column)

open access: yesRevista Derecho del Estado, 2018
How to define sharing benefits from Marine Genetic Resources in the High Seas (water column) as equitable and just? Supposedly, the United Nations Convention on the Law of the Sea, international custom and the Convention on Biological Diversity do not ...
Sergio Peña Neira
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Prospects and Challenges for Harnessing Opportunities in Medicinal Plants Sector in India [PDF]

open access: yesLaw, Environment and Development Journal, 2006
The importance of the medicinal plants sector can be gauged from the fact that herbal medicines serve the healthcare needs of about 80 per cent of the world's population.
Harbir Singh
doaj  

Who Should Benefit from REDD+? Rationales and Realities

open access: yesEcology and Society, 2013
Benefit-sharing mechanisms are a central design aspect of REDD+ because they help to create the necessary incentives to reduce carbon emissions. However, if stakeholders do not perceive the benefit sharing as fair, the legitimacy of REDD+, and support ...
Cecilia Luttrell   +6 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

An interdisciplinary model for mapping the Normative diffusion of fair and equitable benefit-sharing

open access: yes, 2015
Fair and equitable benefit-sharing is emerging in various areas of international environmental law (biodiversity, oceans, climate change, water, food and agriculture), as well as in international processes on human rights and corporate accountability ...
Louisa Parks (17164909)   +1 more
core   +5 more sources

How to make benefit-sharing possible: the absence of a disclosure of origin system under the BBNJ agreement and the way forward

open access: yesFrontiers in Marine Science
The entry into force of the Biodiversity Beyond National Jurisdiction (BBNJ) Agreement institutionalizes benefit-sharing for marine genetic resources from the high seas.
Fanyu Kong
doaj   +1 more source

Sharing the benefits in IBD [PDF]

open access: yesScience-Business eXchange, 2008
Researchers have demonstrated for the first time a mechanism by which deficiencies in commensal bacteria could contribute to autoimmune disorders such as inflammatory bowel disease. But linking a single type of bacteria or bacterial molecule to human IBD will be challenging.
openaire   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Non-state Actors and the Access and Benefit Sharing issue

open access: yes, 2011
Access and benefit sharing from the use of genetic ...
Orsini, Amandine   +1 more
core  

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