Results 161 to 170 of about 8,561,878 (291)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

89 Stroke Prevention in Atrial Fibrillation and Flutter - Targeting the Untreated Patients In Veterans Health Administration with a Pharmacists-Led, Multi-Center Electronic Health Record Intervention (SPAFF-TNT)

Research and Practice in Thrombosis and Haemostasis
Arthur Allen, Jeffery Kibert, Geoffrey Barnes, Michael Dyal, Paul Varosy, David Parra   +5 more
doaj   +1 more source

Efficient use of prohexadione-Ca in pome fruits

European Journal of Horticultural Science, 2003
W. Rademacher, R. Kober
doaj   +1 more source

Nontuberculous mycobacterial pulmonary disease: a nationwide cost analysis of healthcare costs, foregone earnings and public benefits in a universal healthcare setting. [PDF]

ERJ Open Res
Dahl VN, Pedersen AA, Ibsen MH, Hilberg O, Løkke A, Fløe A.   +5 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Cost-benefit analysis of adolescent HIV/STI prevention and comprehensive sexuality education interventions in Cambodia: a modelling study. [PDF]

BMJ Public Health
Wickramaarachchi T, Phon V, Bernklau S, Sladden T, Martin-Hughes R, Scott N.   +5 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Influence of organizational atmosphere on current and future professional benefits among staff nurses: a cross-sectional study. [PDF]

BMC Nurs
Ebraheem SMA, Elborai ASA, Gaber MAE, Ali EHM.   +3 more
europepmc   +1 more source

Optical Benefits [PDF]

British Journal of Ophthalmology, 1925
openaire   +2 more sources

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source