Results 271 to 280 of about 2,274,656 (330)

A prognostic nomogram to predict clinical outcomes of patients with primary malignant and benign retroperitoneal tumors. [PDF]

Discov Oncol
Zhang Y, Wu J, Tuersunmaimaiti A, Yao G, Fulati X, Azhati Y, Mamuti A, Li T, Tuxun T.   +8 more
europepmc   +1 more source

Nociceptive Nerve‐Derived CGRP Exacerbates Uterine Fibrogenesis in Adenomyosis by Promoting CD140b+ CD146+ Fibroblast Differentiation

Advanced Science, EarlyView.
This study investigates adenomyosis fibrosis in relation to nociceptive nerves. Nociceptive nerve‐secreted CGRP promotes RAMP1hi CD140b+ CD146+ fibroblast differentiation into myofibroblasts through ERK activation, causing severe fibrosis. Rimegepant‐induced CGRP/RAMP1 signaling blockade alleviates fibrosis and restores fertility in a mouse model. This
Zi Ye, Anning Zhao, Xia Li, Yanqing Hao, Dong Huang, Jianmin Chen, Tiantian Li, Yangyang Dai, Wenchao Sun, Lie Ma, Songying Zhang, Liaobing Xin   +11 more
wiley   +1 more source

YOLO AI model based on an automated breast volume scanner for the detection of benign and malignant breast lesions. [PDF]

Quant Imaging Med Surg
Ma Q, Wang J, Dong B, Yang J, Zhou W, Zhang D, Cheng D, Qin X, Zhang H, Jiang F, Zhang C.   +10 more
europepmc   +1 more source

Novel Evolutionarily Conserved Oncogene COA4 is Driven by KRAS Mutant and Promotes Cancer Metastasis Through Dual Mitochondrial Metabolism‐Dependent and ‐Independent Mechanisms

Advanced Science, EarlyView.
In KRAS‐mutant tumors, KRAS transcriptionally upregulates COA4 via the PI3K/AKT/E2F1 axis, promoting metastasis. Mechanistically, COA4 enhances tumor cell migration through dual pathways: within mitochondria, it boosts oxidative phosphorylation; in the cytoplasm, it binds and activates CDC42 to stimulate pseudopodia formation.
Xingzhao Ji, Weiying Zhang, Fuyuan Xue, Jiazhen Zeng, Qinghua Zhao, Xiaoming Sun, Jian Sun, Heng Zhou, Quanlin Xu, Guoyuan Ma, Shengnan Sun, Ying Wang, Qian Mu, Yi Liu, Qiang Wan   +14 more
wiley   +1 more source

Tissue-Specific Genomic Evolution Despite Shared MED12 Mutations in Benign Tumors. [PDF]

J Clin Med
Namkung J, Park SH, Hwang A, Seo H, Park J, Lee M, Kim H, Choi J, Song JY.   +8 more
europepmc   +1 more source

Nanofluid‐Enhanced Laser Lithotripsy Using Conducting Polymer Nanoparticles

Advanced Science, EarlyView.
Incorporating polymeric nanoparticles, PEDOT:PSS, with a high near‐infrared absorption coefficient into the fluid significantly enhances the dusting efficiency of Ho:YAG laser lithotripsy for kidney stone treatment. This approach, which leverages the control of light‐matter interactions, integrates seamlessly with the current laser lithotripsy workflow.
Qingsong Fan, Junqin Chen, Arpit Mishra, Aaron Stewart, Faisal Anees, Ting‐Hsuan Chen, Judith Dominguez, Christine Payne, Michael E. Lipkin, Pei Zhong, Po‐Chun Hsu   +10 more
wiley   +1 more source

Occult MALT lymphoma masquerading as benign cysts in Sjögren's syndrome: A case report of diagnostic dilemma. [PDF]

Int J Surg Case Rep
Alkheder A, Azar A, Mustafa A.
europepmc   +1 more source

Tumor‐Targeted FABP5/STING Cascade Promote Radiofrequency Ablation Induced Ferroptosis and Intratumoral Immune Rewiring in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Targeted FABP5 co‐delivery nanoparticles amplify RFA‐induced ferroptosis and intratumoral immune rewiring via STING/TBK1 pathway activation in HCC. The pH‐responsive lipid nanoshell was integrated with cyclic RGD peptide (cRGD) and red blood cell membrane (RBCM), and encapsulated with superparamagnetic iron oxide (SPIO) and sgFABP5 to construct FS@RBCM/
Bufu Tang, Xiaojie Zhang, Yiting Sun, Jinhua Luo, Qiaoyou Weng, Cong Zhang, Zilin Wang, Shiji Fang, Yangrui Xiao, Liyun Zheng, Jianfei Tu, Rongfang Qiu, Yang Yang, Zhongwei Zhao, Weiqian Chen, Minjiang Chen, Jiansong Ji   +16 more
wiley   +1 more source

Well-Differentiated Spindle Cell Liposarcoma of the Larynx in a Patient With a History of a Benign Laryngeal Lesion: A Case Report. [PDF]

Cureus
Watson MI, Otto AL, Hansen R, McIntire K.   +3 more
europepmc   +1 more source

Iron Single‐Atom Catalyzed N‐Alkylation of Amines with Alcohols via Solvent‐Free Borrowing Hydrogen Strategy

Advanced Science, EarlyView.
An innovative iron‐based single‐atom catalyst (FeSA@N‐G) with Fe1–N4 coordination is presented, synthesized through a simple and scalable method. It exhibits exceptional activity and selectivity in N‐alkylation via the borrowing hydrogen strategy under solvent‐free conditions, producing water as the only by‐product. Achieving record TOF (413.1 h-1) and
Arun D. Kute, Hanumant B. Kale, Priti Sharma, Srinivasu Kancharlapalli, Gajanan Y. Shinde, Ruchi Chauhan, Ajay K. Singh, Shan Jiang, Jeffrey T. Miller, Radek Zboril, Yifeng Wang, Manoj B. Gawande   +11 more
wiley   +1 more source