Results 21 to 30 of about 315,046 (257)

Evaluation of the expression pattern and diagnostic value of PPARγ in malignant and benign primary bone tumors

BMC Musculoskeletal Disorders, 2022
Purpose The quantifiable description of PPARγ expression pattern beside mechanistic in-vitro evidence will provide insights into the involvement of this mediator in tumor pathogenesis.
Amir Reza Eghtedari, Mohammad Amin Vaezi, Banafsheh Safizadeh, Ghasem Ghasempour, Pegah Babaheidarian, Vahid Salimi, Masoumeh Tavakoli-Yaraki   +6 more
doaj   +1 more source

Soft tissue chondromyxoid fibroma.An extremely rare case

Journal of the Bulgarian Orthopaedics and Trauma Association, 2023
Chondromyxoid fibroma is a rare benign bone tumor that accounts for less than 1% of primary bone tumors. The soft tissue variant of this tumor is extremely rare. Herein, we present a case of soft-tissue chondromyxoid fibroma in the foot of a 13-year-old
Luben Stokov, Spas Krustev, Georgi Georgiev , Luben L.Stokov   +3 more
doaj   +3 more sources

Prevalence of bone and soft tissue tumors

Acta Orthopaedica et Traumatologica Turcica, 2020
Objective: Multidisciplinary approach is a necessity for the appropriate diagnosis and treatment of bone and soft tissue tumors. The Ege University Musculoskeletal Tumor Council offers consultation services to other hospitals in the Aegean region.
Guven Yuceturk, Dundar Sabah, Burcin Kececi, Ahmet Duran Kara, Selcuk Yalcinkaya   +4 more
doaj   +1 more source

Demographic and clinical characteristics of patients with benign bone tumors: Evidence of bimodal age distribution in a Hispanic population

Journal of Orthopaedic Reports
Background: As far as researchers know, there's no way to prevent BBTs from forming. Although these tumors generally do not metastasize, they can still be dangerous as they may grow and compress healthy tissues and lead to poor outcomes.
Blake C. Martin, Mohammad Khalil, Juan Lopez-Alvarenga, Michael Sander   +3 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Biomass DNA: An Emerging Building Block for Advanced Materials

Advanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

Osteoid osteoma: Contemporary management

Orthopedic Reviews, 2018
Osteoid osteoma is a benign bone-forming tumor with hallmark of tumor cells directly forming mature bone. Osteoid osteoma accounts for around 5% of all bone tumors and 11% of benign bone tumors with a male predilection.
Shahryar Noordin, Salim Allana, Kiran Hilal, Naila Nadeem, Riaz Lakdawala, Anum Sadruddin, Nasir Uddin   +6 more
doaj   +1 more source

Percutaneous Treatments of Benign Bone Tumors [PDF]

Seminars in Interventional Radiology, 2018
AbstractBenign bone tumors consist of a wide variety of neoplasms that do not metastasize but can still cause local complications. Historical management of these tumors has included surgical treatment for lesion resection and possible mechanical stabilization. Initial percutaneous ablation techniques were described for osteoid osteoma management.
Koch, Guillaume, Cazzato, Roberto Luigi, Gilkison, Andrew, Caudrelier, Jean, Garnon, Julien, Gangi, Afshin   +5 more
openaire   +3 more sources