Results 131 to 140 of about 1,605,836 (247)

Bilateral Breast Gradient Insert Prototype for Strong Diffusion Encoding at 3 T

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Diffusion MRI has shown promise for breast cancer screening, lesion characterization, and treatment response monitoring without contrast agents, but further translation is constrained by the gradient performance of conventional systems.
Gerrit Cornelis Arends, Edwin Versteeg, Feng Jia, Dennis W. J. Klomp, Maxim Zaitsev, Sebastian Littin, Chantal M. W. Tax   +6 more
wiley   +1 more source

Depiction Fidelity and Specificity in Direct MRI of Collagen: Addressing Signal Decay at the Microsecond Timescale

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Gap‐filled zero echo time (ZTE) acquisitions combined with dedicated short‐T2 hardware enable direct collagen imaging on the timescale of macromolecular (MM) signals, with T2s ˜ 10 μs. However, present methods offer limited depiction fidelity, and their specificity towards MM content is poorly understood. This work presents methodology
Jason Daniel van Schoor, Markus Weiger, Emily Louise Baadsvik, Klaas Paul Pruessmann   +3 more
wiley   +1 more source

Bone tumor in the pediatric age

Archivo Médico de Camagüey, 2019
Background: bone tumors are sometimes difficult to diagnose, they are divided into benign and malignant, benign tumors are the most frequent and among them the Osteochondroma is the main one.
Eugenio Isidro Rodríguez-Rodríguez, Leonardo Taura-Suárez   +1 more
doaj  

Primary and Secondary Implantation in Mandibular Reconstruction: A Systematic Review and Meta‐analysis

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To identify clinical factors influencing implant placement/timing decisions, through comparing survival, success, and complication rates of primary and secondary dental implantation following mandibular reconstruction. Data Sources A systematic search was conducted in the PubMed, Embase, and Cochrane Central Register of Controlled ...
Laura Zsófia Tasi, Ábel Major, Alexander Schulze Wenning, Tamás Würsching, Gábor Gerber, Árpád Joób‐Fancsaly, Enikő Vasziné Szabó, Anna Walter, Péter Hegyi, Kinga Körmöczi, Tamás Huszár   +10 more
wiley   +1 more source

Sickle Cell Disease: Historical Overview and Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Applications and prospects of artificial intelligence and digital medicine in pediatric nasal skull base tumors

Pediatric Investigation, EarlyView.
Pediatric nasal skull base tumors present diagnostic and therapeutic challenges due to their deep location, nonspecific symptoms, and the narrow nasal cavity in children. Although artificial intelligence (AI) and digital medicine have advanced early diagnosis, multidisciplinary treatment, and prognosis, their application in these rare tumors remains ...
Xiuping Wu, Jing Wei, Chen Liu, Pengpeng Wang, Wentong Ge, Yang Han   +5 more
wiley   +1 more source

Human Prostate Cell Lines: Derivation, Molecular Characteristics and Appropriate Use

The Prostate, EarlyView.
ABSTRACT Background Research on prostate cancer and benign prostatic hyperplasia depends on a small number of immortalized human cell lines established between 1977 and 2001, most of them from advanced metastatic disease. The cell lines differ from one another in androgen receptor status, prostate‐specific antigen secretion, p53 status, karyotype and ...
Hamza Abohamra, Keenau Mark Pearce
wiley   +1 more source

Real‐World HRR Testing Pathways and Patterns of Detected Alterations in Prostate Cancer From the Multinational ARON‐3 Study

The Prostate, EarlyView.
ABSTRACT Background Homologous recombination repair (HRR) testing is increasingly relevant in prostate cancer because it identifies patients who may benefit from biomarker‐guided treatment strategies, including poly(ADP‐ribose) polymerase inhibitors (PARPi).
Lorena Incorvaia, Veronica Mollica, Ondřej Fiala, Kazutoshi Fujita, Yüksel Ürün, Bohuslav Melichar, Javier Molina‐Cerrillo, Teresa Alonso‐Gordoa, Umberto Basso, Maria T. Bourlon, Emmanuel Seront, Ugo De Giorgi, Maria José Juan Fita, Pasquale Rescigno, Tarek Taha, Fernando C. Maluf, Alexandr Poprach, Simona De Summa, Tomas Buchler, Luca Galli, Jindrich Kopecky, Gaetano Aurilio, Jakub Kucharz, Carlo Messina, Gabriel Berlingieri Polho, Sarah Scagliarini, Francesco Grillone, Diogo Assed Bastos, Luigi Formisano, Gian Paolo Spinelli, Alessandra Mosca, Alessandro Rizzo, Aristotelis Bamias, Fernando Sabino Marques Monteiro, Andrey Soares, Francesco Massari, Andrew J. Armstrong, Matteo Santoni   +37 more
wiley   +1 more source

Engineering metal‐organic framework‐based smart porous nanoplatforms for targeted therapy and theranostic applications

Smart Molecules, EarlyView.
MOFs offer high porosity and tunability for biomedical applications, especially in cancer therapy via ROS generation and targeted delivery. Though toxicity, stability, and scalability remain key clinical challenges. Drug loading in MOFs exceeds 60%–70% with controlled release behavior.
Jagabandhu Bag, Subhasis Banerjee, Sabyasachi Banerjee, Sourav De, S. K. Ashok Kumar, Yan‐Jye Shyong, Subhankar Mukhopadhyay   +6 more
wiley   +1 more source

Sustainable and Programmable Hydrogels for Bone Regeneration: A Perspective on Green Synthesis and Precision Fabrication

SusMat, EarlyView.
The clinical translation of natural hydrogels is often hindered by a fundamental conflict. Green synthesis prioritizes biosafety through mild and non‐toxic conditions, whereas precision manufacturing demands mechanical robustness and structural fidelity.
Jiaxin Wu, Xu Wang, Hanfei Li, Xibo Pei, Hao Feng, Jian Wang   +5 more
wiley   +1 more source