Results 41 to 50 of about 405,701 (281)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hemodynamic indicators of doppler test within arteria profunda linguae in patients with combined pathology of mucous membrane of oral cavity and rheumatoid arthritis

Zaporožskij Medicinskij Žurnal, 2017
Objective: The purpose of this study was to investigate hemodynamic in arteria profunda linguae with the help of Doppler ultrasonography in triplex scanning mode in patients with pathology of mucous membrane of oral cavity and combined rheumatoid ...
A. V. Povsheniuk , B.Yu. Komnatskyi, V. M. Kulygina, E. V. Beliaiev   +3 more
doaj   +1 more source

Cultural traditions across a migratory network shape the genetic structure of southern right whales around Australia and New Zealand [PDF]

, 2015
ELC was supported by the AMMC and a Newton Fellowship from the Royal Society and RH in part by a Sitka Sound Science Centre Scientist in Residency Fellowship. OEG acknowledges support from the MASTS pooling initiative (The Marine Alliance for Science and
Carroll, Emma Louise, Gröcke, D. R., J. Bannister (3245850), Harcourt, Robert, R. Alderman (3245853), Alderman, Rachael, Gröcke, Darren, O. E. Gaggiotti (3245862), E. L. Carroll (12840311), Baker, C. Scott, Gaggiotti, O.E., Patenaude, Nathalie, Watson, M., Baker, C. S., M. Watson (3245868), N. Patenaude (3245865), Gröcke, D.R., Gaggiotti, Oscar Eduardo, D. R. Gröcke (3245856), Gaggiotti, O. E., Patenaude, N., Harcourt, R., Watson, Mandy, C. S. Baker (12840314), Baker, C.S., Bannister, John, Alderman, R., Bannister, J., Carroll, E.L., R. Harcourt (3245859), Carroll, E. L.   +30 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Personality traits in resident and migratory warbler species. [PDF]

, 2005
Animals are often confronted with environmental challenges and the way in which they cope with these challenges can have important fitness consequences.
Steiger, S., Schmidt, T., Ebert, C., Mettke-Hofmann, C., Stieb, S.   +4 more
core   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Migratory Bird Conservation Commission: A Legacy of Conserving Habitat for Migratory Waterfowl

, 2017
Migratory Bird Conservation Commission footage on the history, future, and impacts of their conservation program for migratory waterfowl habitats.https://deepblue.lib.umich.edu/bitstream/2027.42/139159/2/0003.ziphttps://deepblue.lib.umich.edu/bitstream ...
Dingell, John D.
core   +5 more sources

Diabetes and Oral Health: Summary of Current Scientific Evidence for Why Transdisciplinary Collaboration Is Needed

Frontiers in Dental Medicine, 2021
This Perspective provides a brief summary of the scientific evidence for the often two-way links between hyperglycemia, including manifest diabetes mellitus (DM), and oral health.
Wenche Sylling Borgnakke, Prakash Poudel, Prakash Poudel   +2 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source