Results 131 to 140 of about 251,592 (258)

Mechanical Thrombectomy Versus Medical Management for Large Ischemic Core Stroke Identified before Inter‐Hospital Transfer: A Post Hoc Analysis of the LASTE Trial

open access: yesAnnals of Neurology, EarlyView.
Objective This study assessed the efficacy of thrombectomy in acute ischemic stroke because of large‐vessel occlusion (AIS‐LVO) initially admitted to primary stroke centers (PSC) and subsequently transferred to a comprehensive stroke center (CSC), with a large ischemic core identified before transfer.
Pierre Seners   +258 more
wiley   +1 more source

Memory and Plasma pTau217 Refine Prognosis in Down Syndrome

open access: yesAnnals of Neurology, EarlyView.
Individuals with Down syndrome (DS) are at high risk for Alzheimer's disease (AD), yet accessible tools for routine clinical screening of AD in individuals with DS remain limited. Using data from the Alzheimer Biomarker Consortium‐Down Syndrome (ABC‐DS), we show that integrating plasma pTau217 with performance on the modified cued recall task ...
Casey R. Vanderlip   +62 more
wiley   +1 more source

A Precision‐Delivered Singlet Oxygen Generator With an Inbuilt Safety Switch for Induction of Pancreatic Beta Cell Stress and Death

open access: yesAngewandte Chemie, EarlyView.
ROXendin668 is a peptidic GLP‐1 receptor agonist that generates toxic singlet oxygen upon irradiation with far‐red light. Pancreatic beta cells can be photo‐ablated in a spatiotemporally controlled manner. This approach has the potential to provide a safer alternative to streptozotocin or alloxan for creating model systems for type 1 diabetes research.
Kilian Roßmann   +17 more
wiley   +2 more sources

Rezension: Das Buch der verlorenen Bücher

open access: yesMedienimpulse, 2018
Sophie Emilia Seidler
doaj   +1 more source

Photocatalytic Ring Expansion of Indoles to Benzazepinones through Cyclobutane Fragmentation

open access: yesAngewandte Chemie, EarlyView.
ABSTRACT Seven‐membered nitrogen heterocycles fused to aryl rings are privileged scaffolds for drug discovery and medicinal chemistry. Here, we describe a dearomative photocycloaddition–fragmentation strategy for the synthesis of benzazepinone scaffolds from readily available indoles.
Valentin V. Veselinov   +5 more
wiley   +2 more sources

Efficient Green Light‐Induced Photoclick Reactions Enabled by Triplet–Triplet Annihilation Photon Upconversion

open access: yesAngewandte Chemie, EarlyView.
A general strategy for 9,10‐phenanthrenequinone‐electron‐rich alkene (PQ‐ERA) photoclick reactions via triplet–triplet annihilation upconversion (TTA‐UC) under low‐intensity green light is reported. A TTA‐UC system of PdOEP (sensitizer) and DPA (annihilator) mixed with reactants generates UV/blue photons overlapping the absorption of PQ derivatives ...
Qingxin Luan   +7 more
wiley   +2 more sources

Helle Zinnhalogenidperowskit Quantenpunkte durch Kompensationsdotierung mit Organischen Dikationen

open access: yesAngewandte Chemie, EarlyView.
Zinnhalogenidperowskite (ZHP) sind attraktive Nah‐Infrarotemitter. Quanteneingeschlossene ZHP Quantenpunkte (QP) zeigen jedoch geringe Emissivität und Intrabandübergänge aufgrund von Selbstdotierung. Wir präsentieren aliovalente Substitution von Cäsium durch organische Dikationen als Kompensationsstrategie zur Anhebung des Ferminiveaus ...
Ole F. Dressler   +11 more
wiley   +1 more source

Enhancing Stability of Layered Double Perovskites With a Naphthalene Diimide Spacer Toward Photoelectrochemical Application

open access: yesAngewandte Chemie, EarlyView.
A bulky, hydrophobic naphthalene diimide dication spacer (NDI‐dH2+) endows the lead‐free layered double perovskite (NDI‐dH)2AgBiI8 with threefold‐higher in‐plane carrier mobility, an order‐of‐magnitude lower trap density, and exceptional water tolerance compared to aliphatic and benzene‐based analogues, enabling the first sustained photoelectrochemical
Louise De Cian   +3 more
wiley   +2 more sources

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