Proceedings of the Eighteenth General Meeting Benjamin Franklin Hotel, Philadelphia, Pa. March 13 and 14, 1940 [PDF]
, 1940 Hamilton B.G. Robinson
openalex +1 more source
Gigaxonin Potentiates Antiviral Innate Immune Responses by Targeting cGAS and TREX1
Advanced Science, EarlyView.TREX1 antagonizes DNA sensor cGAS by degrading cytosolic DNA. This work identifies gigaxonin as a molecular switch that coordinates DNA sensing and clearance pathways to amplify antiviral responses. Under the steady state, gigaxonin maintains cellular homeostasis by mediating TREX1 ubiquitination and proteasomal degradation. During DNA virus infection,
Ben‐Zhe Ji +9 more
wiley +1 more source
From Comte to Benjamin Kidd: The appeal to biology or evolution for human guidance.
, 1899 Robert Mackintosh
openalex +2 more sources
Microphysiological Solid Tumor Models in Hydrogel Beads for CAR T Cell Immunotherapy Evaluation
Advanced Science, EarlyView.The complex physical and biochemical barriers of the tumor microenvironment are major triggers of immune exclusion. Here, a 3D micrometastasis model is developed to mimic key microenvironmental cues, enabling in vitro evaluation of chimeric antigen receptor (CAR) T cell immunotherapy. Abstract Micrometastases are challenging to resect surgically and to
Xuan Peng +14 more
wiley +1 more source
IX. An account of a method of measuring the comparative intensities of the light emitted by luminous bodies. By Lieutenant-General Sir Benjamin Thompson, Count of Rumford, F. R. S. In two letters to Sir Joseph Banks, Bart. P. R. S [PDF]
Bruce Thompson
openalex +1 more source
Advanced Science, EarlyView.A novel multifunctional scaffold with photothermal effects is developed for infected bone defect repair. It facilitates angiogenesis and osteogenesis while eliminating bacteria through hyperthermia. Additionally, the scaffold promotes macrophage polarization from M1 to M2 via ROS scavenging, enhancing anti‐inflammatory activity. This study demonstrates
Qifei Yang +9 more
wiley +1 more source
II. A letter from the Rev. Dr. Samuel Clarke to Mr. Benjamin Hoadly, F. R. S. occasion'd by the present controversy among mathematicians, concerning the proportion of velocity and force in bodies in motion [PDF]
Samuel Clarke
openalex +1 more source
Redescriptions: Political Thought, Conceptual History and Feminist Theory, 2006 openaire +3 more sources
Advanced Science, EarlyView.This study establishes a direct link between photocatalytic activity, spectroscopic properties, and theoretical analysis of structural effects on exciton behavior in ionic carbon nitrides with different cations. The exciton lifetimes and photocatalytic activity are shown to be primarily related to different dark exciton dynamics governed by changes in ...
Arindam Konar +12 more
wiley +1 more source
Advanced Science, EarlyView.Metabolomics‐based ageing clocks developed using blood biomarkers from over 215 000 European adults, improved the prediction of 10‐year all‐cause mortality compared to traditional models. Biological age acceleration is associated with higher mortality risk, as each additional year of metabolic age corresponded to at least 8% increased risk. These tools
Lei Peng +4 more
wiley +1 more source