Results 31 to 40 of about 2,064,304 (288)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Boston University Women's Chorale, Concert Choir, and Chamber Chorus, March 31, 2007 [PDF]

open access: yes, 2007
This is the concert program of the Boston University Women's Chorale, Concert Choir, and Chamber Chorus performance on Saturday, March 31, 2007 at 8:00 p.m., at Marsh Chapel, 735 Commonwealth Avenue, Boston, Massachusetts.
School of Music, Boston University
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Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Singularity, violence and universality in Derrida’s ethics: Deconstruction’s struggle with decisionism [PDF]

open access: yesFilozofija i Društvo
The starting point of the paper is Derrida’s early discussion of Lévinas, focusing on the suggestion that violence is paradoxically magnified in Lévinas’s attempt to articulate ethics as first philosophy within a metaphysics ostensibly free of ...
Stocker Barry
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann   +17 more
wiley   +1 more source

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer   +11 more
wiley   +1 more source

Benjamin’s KISS: A Perspective on Music, Spectacle and Aura [PDF]

open access: yesIASPM Journal, 2016
This article explores the ontological significance of spectacle and imagery in rock music. The examination illuminates how the construct of a larger-than-life fantasy and a live performance spectacle creates a sense of auratic presence; in other words ...
Rob Ahlers
doaj   +1 more source

Performance Characteristics of Anti–Collagen II Antibodies in Relapsing Polychondritis and Related Diseases: Prospective Analysis, Systematic Review, and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective Relapsing polychondritis (RP) is a rare disease defined by recurrent cartilaginous inflammation. Anti–collagen II (Col2) antibodies have been proposed as a diagnostic biomarker for RP, but their performance characteristics are not well defined.
Karyssa Stonick   +6 more
wiley   +1 more source

PENGARUH KONFLIK TERHADAP KINERJA KARYAWAN PADA PERUSAHAAN SENAPAN ANGIN BENYAMIN COBRA SATRIA PARE KEDIRI [PDF]

open access: yes, 2010
The purpose of this study is to determine how conflicts between individuals and between groups and the performance of employees at the company's air rifle "Cobra Benjamin Satria" Pare Kediri.
AHMAD ZAENAL, ARIFIN
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