Relationship between Electronic Structure and Cytotoxic Activity of Azulenequinones and Trihaloacetylazulenes [PDF]
, 2007 The relationship between the structure and cytotoxicactivity of azulenequinones and trihaloacetylazulenes wasinvestigated based on theoretical calculations.
佐藤, 理絵 +5 more
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Control of serotonergic neurons in rat brain by dopaminergic receptors outside the dorsal raphe nucleus [PDF]
, 2001 We studied the control of dorsal raphe (DR) serotonergic neurons by dopaminergic transmission in rat brain using microdialysis and single unit extracellular recordings. Apomorphine (0.5–3.0 mg/kg s.c.) and quinpirole (0.5 mg/kg s.c.) increased serotonin (
Artigas, Francesc +4 more
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Inhibition of 6-hydroxydopamine-induced oxidative damage by 4,5-dihydro-3H-2-benzazepine N-oxides [PDF]
, 2008 A number of new analogs of 3,3-dimethyl-4,5-dihydro-3H-2-benzazepine 2-oxide, structurally related to the nitrone spin trap α-phenyl-N-tert-butylnitrone (PBN), were synthesized and evaluated for their activity in vitro as protectants against oxidative ...
Altomare, Cosimo +7 more
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The 5-HT2C receptor agonist, lorcaserin, and the 5-HT6 receptor antagonist, SB-742457, promote satiety; a microstructural analysis of feeding behaviour [PDF]
, 2015 RATIONALE: Whilst the FDA-approved anorectic, lorcaserin and various 5-hydroxytryptamine (5-HT)6 receptor antagonists reduce feeding, a direct assessment of their impact upon feeding behaviour is less clear. We therefore examined the action of lorcaserin
Alison J. Cooper +2 more
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Role of intestinal P-glycoprotein in the plasma and fecal disposition of docetaxel in humans [PDF]
, 2000 Multidrug resistance (MDR)-1-P-glycoprotein (P-gp) is a drug-transporting protein that is abundantly present in biliary ductal cells and epithelial cells lining the gastrointestinal tract.
Brouwer, E. (Eric) +5 more
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Synthesis of alkaloids by a diastereoselective allylation of chiral N-sulfinyl imines [PDF]
, 2016 The indium-promoted allylation of chiral N-sulfinyl imines represents a useful and versatile procedure to prepare chiral protected homoallyl amines in a diastereoselective manner. Desulfinylation under acidic conditions liberates easily the corresponding
Foubelo, Francisco, Yus, Miguel
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Candidate 3-benzazepine-1-ol type GluN2B receptor radioligands (11C-NR2B-Me enantiomers) have high binding in cerebellum but not to σ1 receptors [PDF]
, 2022 Lisheng Cai +9 more
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Antipsychotic Drugs Influence Dopamine Neuron Terminals via Action on D2-receptors and Vesicles [PDF]
, 2013 Undergraduate Denman Research Forum - 2nd PlaceDopamine D2 antagonist antipsychotic drugs share the effects of increasing dopamine synthesis, dopamine neuron firing rate, and dopamine and DOPAC levels. These antagonists all raise extracellular dopamine
Klausing, Alex
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Synthetic Approaches Towards Conformationally Constrained Amino Acids
, 2011 This thesis describes research undertaken on the synthesis of conformationally constrained analogues of phenylalanine. The work is introduced by an overview of the significance of conformationally constrained amino acids in chemical biology.
Walke, Amol Ashok, Walke, Amol Ashok
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