Results 81 to 90 of about 2,084 (139)

Fused [1]Benzazepines. Pentacyclic [1]Benzazepines by Reaction of 1H-[1]Benzazepine-2,5(3H,4H)-dione with Aldehydes

HETEROCYCLES, 1995
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
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2-Benzazepines. 5. Synthesis of pyrimido[5,4-d][2]benzazepines and their evaluation as anxiolytic agents

Journal of Medicinal Chemistry, 1983
A series of 5H-pyrimido[5,4-d][2]benzazepines has been synthesized, starting from the corresponding 2-benzazepin-5-ones, and evaluated as potential anxiolytic agents. Selected compounds from this series show a pharmacological profile of action different than that of diazepam. They are more potent than diazepam in the anti-pentylenetetrazole test and in
E J, Trybulski, L E, Benjamin, J V, Earley, R I, Fryer, N W, Gilman, E, Reeder, A, Walser, A B, Davidson, W D, Horst, J, Sepinwall   +9 more
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2‐Benzazepines. 7. Synthesis of pyrimido[5,4‐d][2]benzazepines

Journal of Heterocyclic Chemistry, 1983
AbstractTwo novel syntheses of pyrimido[5,4‐d][2]benzazepines are described. The first synthesis started with 3‐phenylphthalide which in three steps was converted to a functionalized pyrimidine which was cyclized to give the 2‐benzazepine ring system.
James V. Earley, R. Ian Fryer, Norman W. Gilman   +2 more
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The Synthesis of Hydroxytrifluoromethyl 3H-Benzazepines

Synthetic Communications, 1980
Abstract Recent reports have described the dopamine agonist properties of several 7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydrolH-3-benzazepines1. In an attempt to further explore the substitution pattern needed for activity, we required a method for introducing a trifluoromethyl group into the fused aromatic ring and a method for O-demethylation without ...
Dimitri Gaitanopoulos, Martin Brenner
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ChemInform Abstract: 2‐Benzazepines. Part 9. Synthesis and Chemistry of 3H‐2‐Benzazepine and Pyrimido(4,5‐d)(2)benzazepine Derivatives.

ChemInform, 1987
AbstractThe benzazepines (II), prepared from the acetylenes (I), are transformed into the isomeric esters (VI) and (VII) by consecutive bromination, dehydrobromination, and palladium‐catalyzed alkoxycarbonylation.
E. J. TRYBULSKI, R. I. FRYER, E. REEDER, S. VITONE, L. TODARO   +4 more
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Synthesis and Biological Evaluation of Benzazepine Oxazolidinone Antibacterials.

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Paul D, Johnson, Paul A, Aristoff, Gary E, Zurenko, Ronda D, Schaadt, Betty H, Yagi, Charles W, Ford, Judith C, Hamel, Douglas, Stapert, Judy K, Moerman   +8 more
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Synthesis of Benzazepine Analogues of Noscapine

Helvetica Chimica Acta, 1994
AbstractThe synthesis of benzazepine analogues of the opium alkaloid noscapine (1) is described. The benzazepines 2 and 3 were prepared starting from nornarceine ethyl ester (4; readily available from 1) in several steps. X‐Ray analysis of compound 2 revealed that it is not a diastereosisomer mixture but a racemate of the threo‐form and thus has the ...
Helmut Schmidhammer, Eva Scherb‐Bukowiecki, Thomas A. Mayer, Peter Schönholzer   +3 more
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1-Benzazepines. The Synthesis and Reactivity of 2-Chloro-1,5-Dimethyl-1h-1-Benzazepines

Australian Journal of Chemistry, 1986
Treatment of laevulinic acid with N- methylaniline yields 1,5-dimethyl- 1H-1-benzazepin-2(3H)-one and 5-methyl-5-[4-( methylamino )phenyl]-1- phenylpyrrolidin-2-one. The structure of the latter is confirmed by a single-crystal X-ray study. The yield of benzazepinone is increased if either m- methoxy-N-methylaniline or m-methyl-N- methylaniline is ...
JH Bowie, RN Hayes, S Mitkas, RH Prager, MJ Raftery, BW Skelton, MB Stringer, AH White   +7 more
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2‐benzazepines. 10 [1]. New d‐fused 2‐benzazepines

Journal of Heterocyclic Chemistry, 1989
AbstractPyrano[3,2‐d][2]benzazepines were synthesized by reaction of the beta‐dimethylamino unsaturated ketone 1 with malonic ester or the anion of t‐butyl acetate. Conversion of the pyrano derivative to the pyrido[3,2‐d]‐[2]benzazepine was achieved in low yield.
Armin Walser, Louis Todaro
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Synthesis of Dihydro-1-benzazepines

HETEROCYCLES, 2013
A variety of dihydro-1-benzazepines (X) is prepared via a Claisen rearrangement of allyl phenyl ether (III) and a ring-closing metathesis of dienes (IX) as key steps.
Meng-Yang Chang, Chieh-Kai Chan, Shin-Ying Lin   +2 more
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