Results 111 to 120 of about 13,747 (203)
Advanced Science, EarlyView.A retinoic acid receptor agonist, TTNPB, drives the efficient generation of advanced neural stem cells (ANSCs) from human pluripotent stem cells. TTNPB‐centered chromatin remodeling and metabolic reprogramming, promote neuroectoderm commitment. The resulting cells show robust neural potential and functional efficacy in a rat depression model.
Ruilin Du +17 more
wiley +1 more source
Machine Learning for Green Solvents: Assessment, Selection and Substitution
Advanced Science, EarlyView.Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta +4 more
wiley +1 more source
Advanced Science, EarlyView.We have developed a glucose‐triggered on‐demand drug delivery CF‐CPGaMPN hydrogel based on borate ester bonds. It inactivates microbes, releases oxygen, and enables on‐demand drug release in high‐glucose environments to promote healing of diabetic wounds. Single‐cell sequencing reveals that the CF‐CPGaMPN hydrogel significantly alleviates dysfunctional
Manxuan Liu +8 more
wiley +1 more source
Bioinspired Microreactor for Iodide Adsorption and Photooxidation Recovery
Advanced Science, EarlyView.A bioinspired micro‐ionic‐reactor based on porous organic polymer (MIR‐POP) integrates rapid iodide capture with in situ photooxidative conversion, achieving record uptake capacity and high uptake efficiencies in simulated mining wastewater and natural brine. This bioinspired microreactor strategy offers a new avenue for sustainable iodine recovery and
Xuewen Cao +8 more
wiley +1 more source
Advanced Science, EarlyView.A brain‐adhesive sensor (B‐Sensor) was developed by integrating a self‐healing biodegradable elastomer, a tissue‐adhesive hydrogel, and molybdenum electrodes. The B‐Sensor adheres to brain tissue, conforms to cortical curvatures, and maintains stable electrical performance over the intended period for reliable recording of spatiotemporal brain activity
Heewon Choi +8 more
wiley +1 more source
Advanced Science, EarlyView.This study addresses the core scientific question of atomic‐scale structural units and their assembly mechanisms by integrating ion implantation technology— originally developed in nuclear physics research—with flexible intelligent polymers. Through this interdisciplinary approach, we have enabled on‐demand customization of surface functionalities and ...
Yi Chen +11 more
wiley +1 more source
Nanoimprinted DMD Electrodes Enabling Bidirectional Viewing OLEDs With Quasi Lambertian Emission
Advanced Science, EarlyView.We present a dual‐approach strategy for high‐performance bidirectional‐viewing OLEDs, combining enhanced cavity resonance with a nanoimprinted dielectric/metal/dielectric (DMD) electrode. This bidirectional viewing OLED presents an 89.7% enhanced electrode transmittance, a balanced bidirectional emission ratio with 67.3% total brightness increase, as ...
Ningning Song +7 more
wiley +1 more source
Advanced Science, EarlyView.The versatile CaO2@CuMOF@HAP nanohybrid demonstrates an outstanding MMP9/pH‐triggered release performance for sequential release of osteogenic growth peptide into deep‐seated tumor‐infiltrated bone destruction areas and dual ions into tumor cells, enabling efficient tumor‐associated osteolysis restoration and tumor elimination for more comprehensive ...
Lan Liu +8 more
wiley +1 more source
Advanced Science, EarlyView.A Lewis pair site design strategy was established to construct Cu‐doped Mn‐based amorphous nanozymes, where Mn and oxygen vacancies generate cooperative acid‐base pairs. The resulting multinanozyme integrates glycosidase‐, oxidase‐, and cold‐adapted enzyme‐mimicking activities, enabling cooperative depolymerization of cellulose and hemicellulose ...
Huile Liu +8 more
wiley +1 more source
Advanced Science, EarlyView.Utilizing molecular engineering for network design, three pesticide‐loaded organogels (PLOs) carriers exhibiting varying degrees of flexibility were prepared. The mechanical properties of these carriers, tunable via their network molecular structures, enhance their structural adaptability and retention stability at biological interfaces, thereby ...
Yue Wang +6 more
wiley +1 more source