Results 241 to 250 of about 29,837 (275)

Biochemistry of benzimidazole resistance

Acta Tropica, 1994
Heavy reliance on the benzimidazole (BZ) anthelmintics since their introduction in the 1960's for the control of gastrointestinal parasites of livestock has led to widespread BZ resistance in target parasite species. The BZs exert their primary action by binding to tubulin, the major protein component of microtubules.
E, Lacey, J H, Gill
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Interaction of anthelmintic benzimidazoles and benzimidazole derivatives with bovine brain tubulin

Biochimica et Biophysica Acta (BBA) - General Subjects, 1978
The binding and inhibitory properties of 11 benzimidazoles for bovine brain tubulin were investigated. The effects of the benzimidazoles on the initial rates of microtubule polymerization were determined by a turbidimetric assay. The median inhibitory concentrations (I50) for nocodazole, oxibendazole, parbendazole, mebendazole and fenbendazole ranged ...
P A, Friedman, E G, Platzer
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Prototropism in 2-acetyl benzimidazole and 2-benzoyl benzimidazole

Journal of Photochemistry and Photobiology A: Chemistry, 2005
2-Acetyl benzimidazole (2ABI) and 2-benzoyl benzimidazole (2BBI) are found to show excited state prototropic activities in different solvents of varying pH. The absorption, steady state and time-resolved emission studies were made on the basis of a theoretical possibility study of proton transfer in the excited state.
Papia Chowdhury, Subhasis Panja, Amrita Chatterjee, Pranab Bhattacharya, Sankar Chakravorti   +4 more
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Benzimidazoles: Veterinary uses

Parasitology Today, 1990
Benzimidazoles are valued for use against helminth infections in domestic animals. Here, Bill Campbell discusses efficacy, dosages, methods of administration and the species of parasite against which they are applied.
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Mode of action of benzimidazoles

Parasitology Today, 1990
Benzimidazoles represent the only class of truly broad-spectrum anthelmintics, however, they also show activity against fungi and mammalian cells. This raises the question as to why benzimidazoles can selectively kill helminths and yet exhibit little or no mammalian toxicity.
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Benzimidazoles in a wormy world

Parasitology Today, 1990
The problem of helminth infection is vast by anyone’s reckoning and is of equal interest to the veterinary surgeon and the clinician. To say that helminths are ubiquitous is almost an understatement: as parasites of livestock and humans, they represent the single most important group of infections on the planet, although many separate species are ...
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Oxomolybdenum (V) Complexes of Benzimidazole and 2 - Substituted Benzimidazoles

Synthesis and Reactivity in Inorganic and Metal-Organic Chemistry, 1991
Abstract Oxomolybdenum (V) complexes of the type (LH)2-[MoOCl5], (LH)2 [MoOCl4.OH], (LH)MOOCI4.F2O], [Mo2O4cl-(L - H)L′ (H2O)2-].nH2O, (where L = benzimidazole, 2 - α-hydroxymethyl benzimidazole, 2 - α - hydroxyethyl benzimidazole and 2 - α- hydroxybenzyl benzimidazole, L″ = EtOH or H2O and n = O, 1 or 2); [MoOCl3(L)2]H2O, (L = benzimidazole); [MoOCl2 ...
S. R. Girish, V. B. Mahale
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Quinoxaline-benzimidazole rearrangement in the synthesis of benzimidazole-based podands

Russian Journal of Organic Chemistry, 2006
Alkylation of 3-benzoylquinoxalin-2(1H)-one with 1,5-dibromo-3-oxapentane, 1,8-dibromo-3,6-dioxaoctane, and α,ω-dihaloalkanes with different lengths of the polymethylene chain gave the corresponding quinoxaline podands. In the reaction with 1,2-dibromoethane, the N,O-rather than N,N′-alkylation product was obtained.
V. A. Mamedov, A. A. Kalinin, A. T. Gubaidullin, E. A. Gorbunova, I. A. Litvinov   +4 more
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Iron–sulphur dimers with benzimidazolate–thiolate, benzimidazolate–phenolate, or bis(benzimidazolate) terminal chelating ligands

J. Chem. Soc., Chem. Commun., 1986
[Fe2S2L2]2– complexes co-ordinated by the mixed-donor N–S, N–O, or N–N ligands L1–L4 are characterised by electronic and n.m.r. spectroscopy and shown to undergo one-electron reduction to the corresponding trianions with e.s.r. spectra exhibiting a range of g-tensor values which are compared with those for [2Fe–2S]+ proteins of the Rieske type.
Peter Beardwood, John F. Gibson
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Poly(benzimidazole)

2009
Abstract Major Applications Fire-resistant material, replacement for asbestos, thermal-protective clothing, ion-exchange resins, microporous absorbent beads, membrane applications. Properties of Special Interest High-temperature stability, nonflammability, unusual resistance to organic solvents, excellent mechanical properties ...
Vladyslav Kholodovych, William J Welsh
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