Molecular doping of polymeric semiconductors is a key strategy to tune charge transport properties, energy levels alignment and charge injection in printed electronic devices. N‐type doping is more challenging than p‐type due to the characteristic energy
Francesca Pallini +15 more
doaj +2 more sources
Tumor-Adhesive Chitosan-Derived Multi-Immune Agonist Unleashes Strong and Durable Anti-Cancer Immunity. [PDF]
A tumor‐adhesive chitosan‐derived immune agonist TACTIC is developed for strong and durable anti‐tumor immunity. The immune agonist exhibits multi‐targets and modulates both tumor cell immunogenicity and pro‐inflammatory responses in immune cells, thereby potentiating the therapeutic efficacy of clinical radiotherapy.
He H +8 more
europepmc +2 more sources
A Comprehensive Review of Acne Treatments: Unpacking the Chemical Structures and Effective Bioactive Compounds. [PDF]
ABSTRACT Background and Aims Acne vulgaris is a frequent skin disorder, affecting a large part of the population worldwide, and strongly influencing not only the physical but also the mental aspects of health. The choice of therapy for acne vulgaris is a very difficult one because the multifactorial causality of the disease and interindividual ...
Tajdari M +5 more
europepmc +2 more sources
Modulation of the fluorescence of graphene oxide micro-flakes with addition of peripheral benzimidazole group. [PDF]
A new graphene oxide flake with emission from the particle rim is obtained by the presence of peripheral benzimidazole groups. Abstract Graphene oxide (GO) is peripherally modified with the addition of 4‐(1H‐benzimidazol‐2‐yl) benzaldehyde using a Debus–Radziszewski reaction with its ortho‐quinone groups.
Moura HLB, Gehlen MH.
europepmc +2 more sources
Dihalogens Binding and Activation by Imidazoline-2-Chalcogenone Model Derivatives: Insight from a Computational Approach. [PDF]
1,3‐dimethyl‐4‐imidazoline‐2‐chalcogenones react with dihalogens, initially forming a charge‐transfer (CT) adduct, which may evolve to the most stable T‐shaped hypercoordinate (TY) species. However, in silico results show that the CT adduct is more stable than the corresponding TY species for the sulfur and iodine combination.
Zeppilli D +5 more
europepmc +2 more sources
Multifaceted Analysis of Lactobacillus plantarum DMR14 Reveals Promising Antidiabetic Properties Through In Vivo Assays and Molecular Simulations. [PDF]
ABSTRACT Due to the growing concern about diabetes worldwide, we investigated the antidiabetic potential of Lactobacillus plantarum DMR14, assessing its effects on the diabetic mice and identifying safe, bioactive compounds targeting DPP4 protein for drug development through various methods, including in vivo assays, GC–MS analysis and molecular ...
Islam S +7 more
europepmc +2 more sources
2,3-Dihydrobenz[4,5]imidazo[2,1-b]thiazole
The asymmetric unit of the title compound, C9H8N2S, consists of two independent molecules (A and B) differing in the conformation of the thiazole ring: twisted for molecule A and planar for molecule B.
Ahmed Moussaif +4 more
doaj +1 more source
3-(2,4-Difluorophenyl)-1-(pyridin-4-yl)benzo[4,5]imidazo[1,2-d][1,2,4]triazin-4(3H)-one
In the title compound, C20H11F2N5O, the central 13-membered ring system (r.m.s. deviation = 0.028 Å) makes a dihedral angle of 53.13 (7)° with the difluorophenyl ring and 79.98 (7)° with the pyridine ring.
Bassam Abu Thaher +3 more
doaj +1 more source
A new Co(II) perchlorate complex of the bis-morpholino/benzoimidazole-s-triazine ligand, 4,4′-(6-(1H-benzo[d]imidazol-1-yl)-1,3,5-triazine-2,4-diyl)dimorpholine (BMBIT), was synthesized and characterized.
Saied M. Soliman +8 more
doaj +1 more source
Polo-like kinase 1-inhibitor co-complex structures via the surface-entropy reduction approach and a DARPin-assisted approach. [PDF]
A surface‐entropy reduction approach for human Polo‐like kinase 1 (PLK1) enabled a reproducible and robust crystallization system for this cancer drug target. Co‐crystal structures with representatives of three different small‐molecule inhibitor classes were elucidated.
Eberspaecher U +7 more
europepmc +2 more sources

