European Journal of Histochemistry, 2016 Currently, the Annonaceae family is characterised by the production of acetogenins (ACGs), and also by the biosynthesis of alkaloids, primarily benzylisoquinolines derived from tyrosine.
A.E. Brechú-Franco +3 more
doaj +1 more source
Radiolabeling, biodistribution and gamma scintigraphy of noscapine hydrochloride in normal and polycystic ovary induced rats [PDF]
, 2010 Background Noscapine, an alkaloid from Papaver somniferum, widely used as an antitussive, is being clinically studied in the treatment of polycystic ovary syndrome (PCOS) and a few other cancers primarily because of its anti-angiogenesis properties. With
Anjali Priyadarshani +3 more
core +2 more sources
A divergent approach to benzylisoquinoline-type and oxoaporphine alkaloids via regioselective direct ring metalation of alkoxy isoquinolines [PDF]
, 2015 Supramolecular templating techniques have been widely used to direct the formation of porous materials with the goal of introducing permanent mesoporosity. While surfactant-directed self-assembly has been exploited for inorganic materials such as titania,
Bracher, Franz, Melzer, Benedikt
core +3 more sources
Green Routes for the Production of Enantiopure Benzylisoquinoline Alkaloids [PDF]
International Journal of Molecular Sciences, 2017 Benzylisoquinoline alkaloids (BIAs) are among the most important plant secondary metabolites, in that they include a number of biologically active substances widely employed as pharmaceuticals. Isolation of BIAs from their natural sources is an expensive and time-consuming procedure as they accumulate in very low levels in plant.
Ghirga, Francesca +7 more
openaire +3 more sources
Discovery of a Plant Pictet–Spenglerase With R‐Stereoselectivity
Angewandte Chemie, Volume 138, Issue 20, 11 May 2026.Strictosidine synthases (STRs) are plant Pictet–Spenglerases catalyzing the coupling of a secoiridoid with tryptamine. All previously characterized strictosidine synthases are strictly S‐selective. Here, we report the discovery of Epi‐STR, an R‐selective STR ortholog from the medicinal plant Pogonopus speciosus.
Clara Morweiser +3 more
wiley +2 more sources
A New Benzylisoquinoline of Annona Cherimola
Chemical & Pharmaceutical Research, 2023 (-)-Zishenine (1), a new benzylisoquinoline, has been isolated from the roots of Annona cherimola Mill. (Annonanceae). The structure was characterized and identified by spectral analysis.
Chang CT +7 more
openaire +1 more source
Native proteins in organic chemistry. Recent achievements in the use of non hydrolytic enzymes for the synthesis of pharmaceuticals [PDF]
, 2016 Financial support by the Spanish Ministerio de Economia y Competitividad (MINECO) through the CTQ-2013-44153-P project is grateful acknowledged. M.L.-I.
Gotor Fernández, Vicente +2 more
core +2 more sources
The chemical signatures underlying host plant discrimination by aphids [PDF]
, 2017 The diversity of phytophagous insects is largely attributable to speciation involving shifts between host plants. These shifts are mediated by the close interaction between insects and plant metabolites.
A Cruaud +49 more
core +1 more source
Anticoronavirus Isoquinoline Alkaloids: Unraveling the Secrets of Their Structure-Activity Relationship. [PDF]
Influenza Other Respir VirusesABSTRACT Background Natural alkaloids are a structurally diverse class of bioactive compounds with significant therapeutic potential. This study aimed to evaluate the in vitro antiviral activity of various natural alkaloids against coronaviruses, clarify molecular effects via bioassays and docking, and explore structure–activity relationships.
Safratova M +11 more
europepmc +2 more sources
Ammonia borane as a reducing agent in organic synthesis [PDF]
, 2020 Ammonia borane NH3·BH3 is considered a promising material for hydrogen storage and release, and is attracting increasing attention as a relatively inexpensive, atom economy-convenient and viable reagent for developing new green synthetic transformations.
Benaglia M. +3 more
core +1 more source