Abstract figure legend Catecholaminergic polymorphic ventricular tachycardia (CPVT) variants in N terminal (NTD) and central domain (CD) but not pore domain induce a pathological RyR2 conformational shift upon protein kinase A (PKA) phosphorylation, similar to that seen in heart failure (HF), calcium/calmodulin‐dependent protein kinase II (CaMKII ...
Hitoshi Uchinoumi +11 more
wiley +1 more source
O-band DWDM data transmission with quantum dot mode-locked comb laser and semiconductor optical amplifier. [PDF]
Belykh VV +7 more
europepmc +1 more source
14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley +1 more source
Accurate classification and prediction of knee osteoarthritis based on Al-Biruni Earth Radius metaheuristic optimizer and LSTM classifier. [PDF]
Diab AG +4 more
europepmc +1 more source
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley +1 more source
Berberine protects against hypoxia-induced intestinal injury through modulation of gut microbiota and bile acid metabolism. [PDF]
Zhang H +11 more
europepmc +1 more source
Adaptive WHT Aided QAM for Fading Channels Subjected to Impulsive Noise
The Bit Error Rate (BER) expressions of Walsh-Hadamard Transform (WHT) aided Quadrature Amplitude Modulation (QAM) transmitted in impulsive noise environments are derived.
Choi, Byoungjo, Hanzo, Lajos
core
When NCX switches sides: Experimental and computational insights into Ca2+ regulation in the heart
Abstract figure legend Due to its presence inside the dyadic cleft, Na+/Ca2+ exchanger (NCX) builds a functional unit together with L‐type calcium channels and ryanodine receptors in the dyadic cleft. NCX acts bidirectionally (forward and reverse mode) dependent on extracellular calcium ([Ca2+]o) and sodium ([Na+]o) concentrations and the membrane ...
Wilhelm Neubert +6 more
wiley +1 more source
Advanced channel estimation in OTFS and NOMA using deep bayesian gaussian processes and compressive sensing. [PDF]
Anilkumar N, Sengan S.
europepmc +1 more source

