Results 171 to 180 of about 324,497 (361)

Pulmonary arterial mechanoreceptors mediate sustained sympathoexcitation during high altitude hypoxia in humans

open access: yesExperimental Physiology, EarlyView.
Abstract Sympathetic nervous system activation is a hallmark of high‐altitude hypoxia, yet the afferent mechanisms remain incompletely defined. We examined the relative contributions of pulmonary arterial mechanoreceptors and carotid chemoreceptors – two excitatory pathways co‐activated by hypoxia – to sustained sympathoexcitation at altitude.
Michiel T. Ewalts   +13 more
wiley   +1 more source

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand   +2 more
wiley   +1 more source

Blebbistatin reduces calcium buffering in cardiomyocytes: Consequences for cellular electrophysiology

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Blebbistatin reduces Ca2+ buffering in induced pluripotent stem cell‐derived atrial cardiomyocytes. Blebbistatin, a widely used excitation–contraction uncoupling agent, decreases calcium (Ca2+) buffer affinity (increased buffer dissociation constant), leading to elevated diastolic Ca2+ levels, increased sarcoplasmic reticulum Ca2+
Izzatullo Sobitov   +8 more
wiley   +1 more source

Mathematical model of the zebrafish ventricular cardiomyocyte action potential and calcium transient

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This study presents the development and validation of the first biophysically detailed computational model of the zebrafish ventricular action potential (AP). The model is based on a human cardiomyocyte framework and reparameterized using published and newly generated patch‐clamp recordings of zebrafish ionic currents.
Ludovica Cestariolo   +5 more
wiley   +1 more source

Graph-guided adaptive companding for PAPR reduction in power-domain NOMA systems. [PDF]

open access: yesPLoS One
Kumar A   +4 more
europepmc   +1 more source

BER [PDF]

open access: yes, 2019
openaire   +1 more source

Minimum Bit Error Rate Multiuser Detection in Multiple Antenna Aided OFDM

open access: yes, 2003
In this contribution, we propose a Minimum Bit Error Rate (MBER) multiuser detector for Space Division Multiple Access (SDMA) aided Orthogonal Frequency Division Multiplexing (OFDM) systems. It is shown that the MBER detector outperforms the Minimum Mean
Alias, M.Y.   +3 more
core  

Mechanisms underlying local Ca2+ signalling differences between right and left atrial myocytes at normal and increased frequencies

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Left atrial myocytes have TAT‐associated faster Ca2+ release but are more prone to maladaptation at higher frequencies due to weaker peripheral SR Ca2+ uptake and smaller trigger Ca2+ current. Abstract Changes in heart rate affect Ca2+ signalling and contractility in ventricular muscle, but the effects on atrial Ca2+ signalling ...
Joon‐Chul Kim   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy