Manipulating DNA repair and the DNA damage response to improve cancer therapy. [PDF]
Lan L, Fouquerel E.
europepmc +1 more source
The Supporting Role of Natural Products as Effective Adjuvants in Cancer Immunotherapy
Natural products, as multi‐target and low‐toxicity adjuvants, enhance immune checkpoint inhibitor responses and reduce immune‐related adverse events through T cell reprogramming, microenvironment remodeling, and microbiota‐immune modulation. ABSTRACT Immune checkpoint inhibitors (ICIs) have revolutionized the treatment landscape of malignant tumors ...
Boyang Liu +6 more
wiley +1 more source
Spectral efficient and high data rate ring topology based UWOC system with carrier-free optical add-drop nodes. [PDF]
Armghan A +6 more
europepmc +1 more source
Ecosystem carbon, water, and energy exchange reorganize systematically along climatic gradients from humid to dry conditions. Tapering shapes indicate shifts in the relative importance of environmental drivers and ecosystem fluxes across climate space, with thicker ends representing greater influence or magnitude.
Koong Yi +21 more
wiley +1 more source
Experience of Alternative Technique for Branch Cannulation in Branched Endovascular Aneurysm Repair. [PDF]
Mazzaccaro D +6 more
europepmc +1 more source
ComBat‐Predict Enhances Generalizability of Neuroimaging Models to New Sites
ComBat‐Predict effectively harmonizes data from a new site, improving the applicability of normative models to private data. ComBat‐Predict is available for R in the ComBatFamily package. ABSTRACT Neuroimaging is vital in quantifying brain atrophy due to typical aging and due to neurodegenerative diseases.
Yao Xin +12 more
wiley +1 more source
DNA base lesion-containing G-quadruplex mediates transcriptome reprogramming in EGFR-TKI resistance of non-small cell lung cancer. [PDF]
Jing X +18 more
europepmc +1 more source
Lamin B1 safeguards the B cell genome and shapes lymphoma outcome
Abstract Lamin B1 is a structural component of the nuclear lamina that participates in genome organization and transcriptional control. During adaptive immune responses, B lymphocytes in germinal centers (GCs) undergo clonal expansion and programmed DNA damage at immunoglobulin loci, while simultaneously downregulating Lamin B1.
Filip Filipsky +12 more
wiley +1 more source
Long-Term PET-Nanoplastic Exposure Alters DNA Damage Response Capacity in BEAS-2B Human Bronchial Epithelial Cells. [PDF]
Morataya-Reyes M +7 more
europepmc +1 more source
Paradigm shift: PCR‐free methods reveal 6–15‐fold higher arbuscular mycorrhizal (AM) fungal abundance than metabarcoding, exposing systematic underestimation across decades of research. Predictive power: AM fungal abundance serves as a community‐level trait that predicts crop yield under drought conditions.
Peilin Chen, John W. Taylor, Cheng Gao
wiley +1 more source

