Results 161 to 170 of about 51,162 (293)

Late Holocene moisture variability in Arctic Alaska from chitin δ18O

Boreas, EarlyView.
Amplified warming in the Arctic has resulted in reduced sea‐ice extent, which can impact regional climate dynamics. Elucidating past moisture variability in response to changing temperatures and sea‐ice conditions can offer insight into how anthropogenic climate change may impact Arctic areas such as the Alaskan North Slope in the future. We contribute
Briana A. Edgerton, Melissa L. Chipman
wiley   +1 more source

High sensitivity of Bering Sea winter sea ice to winter insolation and carbon dioxide over the last 5500 years. [PDF]

Sci Adv, 2020
Jones MC, Berkelhammer M, Keller KJ, Yoshimura K, Wooller MJ.   +4 more
europepmc   +1 more source

Safety, tolerability, pharmacokinetics and pharmacodynamics of the spleen tyrosine kinase inhibitor BI 894416 in healthy volunteers and patients with asthma

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Spleen tyrosine kinase (SYK) has broad biological functions in inflammation and immunity. The orally administered SYK inhibitor BI 894416 was investigated in a single‐rising‐dose Phase I study in healthy volunteers and in a combined single‐ and multiple‐rising‐dose Phase Ib study in patients with mild asthma ...
Saskia Carstensen‐Aurèche, Tobias Litzenburger, Dorothy De Sousa, Reinhard Sailer, Ewald Benediktus, Denis Delic, Fabian Müller, Meike Müller, Jens M. Hohlfeld   +8 more
wiley   +1 more source

Genetic evidence of a northward range expansion in the eastern Bering Sea stock of Pacific cod. [PDF]

Evol Appl, 2020
Spies I, Gruenthal KM, Drinan DP, Hollowed AB, Stevenson DE, Tarpey CM, Hauser L.   +6 more
europepmc   +1 more source

Algorithms in Allergy: Hereditary Angioedema

Allergy, EarlyView.
Konrad Bork, Markus Magerl, Emel Aygören‐Pürsün, Henriette Farkas   +3 more
wiley   +1 more source

Early and Sustained Asthma Control and Remission in Real‐World Patients With Severe Eosinophilic Asthma Treated With Benralizumab: XALOC‐2

Clinical &Experimental Allergy, EarlyView.
Real‐world patients with severe eosinophilic asthma treated with benralizumab showed early and sustained improvements in symptoms. Clinically meaningful improvements began as early as one week after benralizumab initiation, regardless of previous biologic use, and further improved over the following year.
Erika Penz, Thomas Rothe, Lieven Dupont, Trung N. Tran, Andrew Menzies‐Gow, Anat Shavit, David Cohen, Tanja Plate, Sheena Kayaniyil, An Herreman, Claudio Schuoler, Benjamin Emmanuel, Marek Lommatzsch   +12 more
wiley   +1 more source

Increasing Filamins A and B in Th2 Lymphocytes as a Therapeutic Opportunity to Attenuate Airway Inflammation in Mice

Allergy, EarlyView.
Léa Chamy, Kilian Maire, Charlotte Hateb, Arun Subramaniam, Safia Deddouche‐Grass, Laurent L. Reber, Pierre G. Lutz, Isabelle Lamsoul   +7 more
wiley   +1 more source

The Role of Emotional Parentification in Linking Psychological Abuse and Parental Conflict to Adolescents' Internalised Problems

Child &Family Social Work, EarlyView.
ABSTRACT Previous studies suggest that emotional parentification contributes to internalised problems in children and adolescents and may be one of the key mechanisms linking adverse family experiences to adolescent internalised problems. Qualitative studies indicate that emotional parentification may emerge as a coping mechanism in response to ...
Luka Stanić
wiley   +1 more source

ENSO's changing grip on Bering Sea ice: The emerging control of the North Pacific meridional mode. [PDF]

Sci Adv
Chen J, Yu JY, Wang C, Liu J, Wang X, Chen S, Zhang L, He Z.   +7 more
europepmc   +1 more source

Contact Allergy to Ingredients of Hair Cosmetics Associated with Occupational and Non‐Occupational Exposure—Trends from 1995 to 2020 in Central Europe, with or without Regulation

Contact Dermatitis, EarlyView.
Among 2678 female hairdressers and 6244 female consumers with contact dermatitis suspected to be related to use of hair cosmetics, including dyes, patch tested in the IVDK between 1995 and 2020, diverging contact allergy trends were observed. In the case of toluene‐2,5‐diamine (PTD) shown in the figure, sensitization was at a stable, high level in ...
Wolfgang Uter, Jakob Ferløv Baselius Schwensen, Brunhilde Blömeke, Olaf Gefeller, Swen M. John, Cara Bieck, Steffen Schubert   +6 more
wiley   +1 more source