Results 141 to 150 of about 399,843 (232)

Enhanced Antibacterial Properties of Lyotropic Liquid Crystalline Nanoparticles via Curvature Modulation

Advanced Science, EarlyView.
Lipid nanostructured particles with increasing negative Gaussian curvature progress from vesicles to P‐cubosomes and D‐cubosomes. This curvature hierarchy enhances interaction with bacterial membranes, promotes membrane remodeling and leakage, and potentiates daptomycin activity against MRSA.
Xiangfeng Lai, Shuhong Wang, Chenguang Ding, Xenia Kostoulias, Anton P. Le Brun, Hsien‐Yi Hsu, Jhih‐Hang Jiang, Yajun Wang, Richard A. Strugnell, Anton Y. Peleg, Hsin‐Hui Shen   +10 more
wiley   +1 more source

Catatonia associated with mosaic 18q deletion syndrome: a case report. [PDF]

BMC Psychiatry
Herscheid AL, Franke C, Cosma NC.
europepmc   +1 more source

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

Advanced Science, EarlyView.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt, Nico Kirsch, Aileen Kerfin, Lars P. Lunding, Dominic Ferber, Hannes Buthmann, Ilka Schreier, Carlotta Bosio, Ann‐Kathrin Dobbelstein, Anna Klawonn, Rebecca C. Coll, Lena Bauernhofer, Sandro Keller, Matthias Geyer, Michael Wegmann, Andra B. Schromm, Günther Weindl   +16 more
wiley   +1 more source

Publisher Correction: Single-cell epigenetic and transcriptomic states across the continuum of monoclonal B cell lymphocytosis to chronic lymphocytic leukemia. [PDF]

Genome Biol
Rathgeber AC, Fernandes SM, Nagler A, Li S, Dorfman DM, Bullinger L, Davids MS, Brown JR, Livak KJ, Ludwig LS, Wu CJ, Penter L.   +11 more
europepmc   +1 more source

Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance

Advanced Science, EarlyView.
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer, Ian de Ridder, Mahjoobeh Ehsani, Marasim Khan, Justin Kale, Lukas P. Frenzel, David Andrews, Spyridoula Karamanou, Ana J. Garcia‐Saez, Geert Bultynck   +9 more
wiley   +1 more source

Targetable alterations and personalized treatment in ameloblastoma: results from a prospective observational precision oncology study. [PDF]

NPJ Precis Oncol
Hofmann E, Abu-Sirhan S, Elsholtz F, Piwonski I, Kreutzer K, Doll C, Joosten M, Möbs M, Busch CJ, Fenske B, Knödler M, Pestana A, Hirschhorn A, Heiland M, Keller U, Keilholz U, Klinghammer K, Rieke DT, Schmidt M.   +18 more
europepmc   +1 more source

B Cells are Activated via a Nanoporous Interface that Stabilizes Microvilli and Engages Mechanosensitive Ion Channels

Advanced Science, EarlyView.
B cells can be activated independently of antigen recognition via mechanical stimulation through nanoporous substrates. Exposure to such substrates induced B cell microvilli extension into the pores, intracellular Ca2+ signaling, phosphorylation of signaling proteins, and CD69 expression.
Nozie D. Aghaizu, Willi Weber, Nadine Strempel, Asya Polat, Enrico Klotzsch   +4 more
wiley   +1 more source

Non‐Destructive, Reference‐Free Quantitative Analysis of TaOx Memristive Devices Using Soft X‐Ray Radiation

Advanced Electronic Materials, EarlyView.
A non‐destructive, quantitative approach has been developed to explore the nanoscale dynamics of TaOx‐based memristive devices. The utilization of nano‐X‐ray fluorescence analysis enables the direct probing of spatially resolved elemental distributions, including those present in buried layers, that are critical for the resistive switching.
André Wählisch, Xin Zheng, Andreas Haidl, Jan Weser, Christian Stadelhoff, Marc Dummin, Leona J. Bauer, Rainer Unterumsberger, Ilia Valov, Burkhard Beckhoff   +9 more
wiley   +1 more source

Transcatheter edge-to-edge mitral repair with a nitinol device in cardiogenic shock on micro-axial flow-pump support: a case report. [PDF]

Eur Heart J Case Rep
Schwarzkopf D, Hinkov H, Lee CB, Klein C, Unbehaun A.   +4 more
europepmc   +1 more source

Monolithic Dispersion Element‐Free Optical Spectrometer Fabricated by Combinatorial Inkjet‐Printing of Metal Halide Perovskites

Advanced Electronic Materials, EarlyView.
This work presents inkjet‐printed MHP photodetectors and optical filters. Three precursor inks enable bandgaps from 1.6–3.1 eV, covering the visible spectrum. Combining detector and filter produces a fully printed, dispersion‐free optical spectrometer with precisely tunable spectral selectivity and a minimum spectral bandwidth of 30 nm.
Vincent R. F. Schröder, Nicolas Frantzscher, Felix Hermerschmidt, Florian Mathies, Eva L. Unger, Emil J. W. List‐Kratochvil   +5 more
wiley   +1 more source