Results 51 to 60 of about 405,602 (197)
CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich +19 more
wiley +1 more source
Impact of Plasma p‐tau181 on Cognition, Motor Phenotypes, and Disease Course in ALS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Phosphorylated tau181 (p‐tau181), an Alzheimer's disease biomarker, was recently evaluated in amyotrophic lateral sclerosis (ALS). We investigated plasma p‐tau181 in 202 ALS/ALS‐FTD patients and 94 healthy controls, assessing cognitive performance, motor function, and longitudinal dynamics.
Elisabeth Kasper +25 more
wiley +1 more source
Nuevas Poligrafías, Revista de Teoría Literaria y Literatura Comparada, 2003 Las estancias de Humboldt en Cuba y la obra sobre la isla que surgió de esas visitas, gozaron en la propia Cuba de un amplio interés. Es notable el papel de Humboldt en la imaginación colectiva de Cuba, así como en su vida intelectual, en su historia así
Oliver Lubrich
doaj +1 more source
Efficacy of Inebilizumab in N‐MOmentum Trial Participants With or Without Prior Immunosuppressants
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT This post hoc analysis examined the impact of prior immunosuppressants on the long‐term efficacy and safety of inebilizumab, a cluster of differentiation 19+ B‐cell–depleting monoclonal antibody, in participants with aquaporin‐4–seropositive neuromyelitis optica spectrum disorder from the N‐MOmentum trial (NTC02200770).
Bruce A. C. Cree +9 more
wiley +1 more source
Isegoría, 2004 El problema de cómo concebir coherentemente la libertad está profundamente enraizado en las obras críticas de Kant y relaciona estrechamente entre sí la epistemología, la ética y la estética, así como la interpretación teleológica de la naturaleza.
Astrid Wagner
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner +14 more
wiley +1 more source
El otro como punto de referencia para la educación en Europa
Revista Española de PedagogíaEn Europa la educación se tiene que convertir en una responsabilidad intercultural que considere las similitudes y diferencias entre las diferentes culturas. Cada cultura es una diversidad profunda.
Christoph Wulf
doaj +1 more source
Advanced Engineering Materials, EarlyView.This study investigates laser‐based oxide removal of Cu inserts in oxygen‐free conditions and examines long‐term oxidation kinetics and surface chemistry under different atmospheres via X‐ray photoelectron spectroscopy. Al–Cu compound casting with differently oxidized surfaces is performed, and intermetallic phase formation, morphology, and thermal ...
Timon Steinhoff +9 more
wiley +1 more source
Gobernando las mentes: Sobre las dimensiones subjetivas de la precarización laboral
Cuadernos de Trabajo Social, 2017 A partir del conflicto generacional entre trabajadores/as de las empresas recuperadas en la Argentina a raíz de la crisis económica de 2001, este trabajo investiga los límites y posibilidades de la movilización obrera en el contexto de la precariedad ...
Beatriz Casas González
doaj +1 more source