Results 61 to 70 of about 687,193 (297)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

University: From History to Philosophy: about the Indispenability of Historical Analysis and philosophical Rethinking of the Idea of ​​ University [PDF]

تاریخ نگری و تاریخ نگاری, 2009
By referring to the history of university in western civilization and the thoughts of French Philosopher, Jacques Derrida, concerning the definition of University, this paper briefly examines the problem concerning university as an institution and as an ...
Hosein Mesbahian
doaj   +1 more source

Urban Areas and Urban–Rural Contrasts under Climate Change: What Does the EURO-CORDEX Ensemble Tell Us?—Investigating near Surface Humidity in Berlin and Its Surroundings

, 2019
Climate change will impact urban areas. Decision makers need useful climate information to adapt adequately. This research aims to improve understanding of changes in moisture and temperature projected under climate change in Berlin compared to its ...
Gaby S. Langendijk, D. Rechid, D. Jacob
semanticscholar   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Objects + Things = Stuff. A Visitor’s Guide to Berlin’s Museum der Dinge

Martor, 2018
Museology has shifted its focus in some places of the world: artefacts and historical objects are being repatriated, returned as permanent loans, institutions are questioning the ownership of indigenous objects, selections are made by kids, and texts are
Jasmina Al-Qaisi
doaj  

Comparison of Prevalence and Outcomes of Pediatric Acute Respiratory Distress Syndrome Using Pediatric Acute Lung Injury Consensus Conference Criteria and Berlin Definition

Frontiers in Pediatrics, 2018
Objectives Our objective was to compare the prevalence and outcomes of pediatric acute respiratory distress syndrome using the Pediatric Acute Lung Injury Consensus Conference (PALICC) criteria and Berlin definitions.
Samriti Gupta, J. Sankar, R. Lodha, S. Kabra   +3 more
semanticscholar   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Inwertsetzung von temporären Räumlichkeiten. Standortstrategien von Pop-up-Restaurants in Berlin

Raumforschung und Raumordnung, 2019
Das junge Phänomen der Pop-up-Restaurants in Berlin ist ein spannendes Beispiel für die Temporalität und Eventisierung von wirtschaftlicher Aktivität. Der Beitrag beschäftigt sich mit den Standortstrategien dieser temporären Gastronomiebetriebe. Mithilfe
Pfeufer Nils, Suwala Lech
doaj   +1 more source

Substance Use and Prevention Programs in Berlin’s Party Scene: Results of the SuPrA-Study

European Addiction Research, 2019
Background: Berlin is internationally known for its nightlife. In a nation-wide and Europe-wide comparison, the use of legal and illegal substances is comparatively higher in Berlin than in other similar cities. However, few data exist about the drug use
F. Betzler, Felicitas Ernst, Jonas Helbig, Leonard Viohl, Lukas Roediger, S. Meister, N. Romanczuk-Seiferth, A. Heinz, A. Ströhle, S. Köhler   +9 more
semanticscholar   +1 more source