Results 91 to 100 of about 179,040,826 (293)

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Ohio attorney's guide to interstate child support

, 1999
Title from cover of PDF document (viewed Nov. 18, 2005).; "Ohio attorneys and the CSEA...
Ohio. Office of Child Support.
core  

Secure care: a question of capacity, autonomy and the best interests of the child. [PDF]

CMAJ, 2020
Hamilton AL, Jarvis DG, Watts BEL.
europepmc   +1 more source

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino, Lavanya Muthukumar, Evan L. Reynolds, Peter Todd, Sinem Ovunc, Sheng Chih Jin, Zitian Tang, Simone Thomas, PNRR Study Group, Ahmet Höke, Brian C. Callaghan, Sarah Berth, Vinay Chaudhry, David Cornblath, Leana Doherty, Lindsey Hayes, Hristelina Ilieva, Thomas Lloyd, Mohammad Khoshnoodi, Brett McCray, Brett Morrison, Bipasha Mukherjee‐Clavin, Lyle Ostrow, Michael Polydefkis, Ricardo Roda, Charlotte Sumner   +25 more
wiley   +1 more source

BEST INTEREST OF THE CHILD IN ISLAMIC FAMILY LAW: INTEGRATING MAQĀṢID AL-SHARĪ‘AH AND DOUBLE MOVEMENT THEORY IN ḤAḌĀNAH CASES

Jurnal Al-Dustur
This study examines the development of ḥaḍānah (child custody) in Indonesian Islamic family law, tracing its shift from classical fiqh principles toward contemporary child-centered standards.
Achmad Kadarisman, Alfarid Fedro, Zainal Arifin   +2 more
doaj   +1 more source

Best Interest of the Child

Polis, 2019
In this paper we aim to discuss the best interest of the child as one of the one of the key principles and priorities to international and domestic law. The purpose of this study is to treat the legal aspect for best interest of the child especially related to adoption institute and on the possibility of children’s adoption by homosexuals ...
openaire   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif, Diane Demailly, Gabriella A. Horvàth, Juan Dario Ortigoza Escobar, Nathalie Dorison, Mayté Castro Jiménez, Cécile A. Hubsch, Thomas Wirth, Gun‐Marie Hariz, Sophie Huby, Morgan Dornadic, Zohra Souei, Muhammad Mushhood Ur Rehman, Simone Hemm, Mehdi Boulaymen, Eduardo M. Moraud, Jocelyne Bloch, Xavier Vasques   +17 more
wiley   +1 more source

Office of the Child Advocate

, 2012
Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed Nov. 7, 2011).; At head of title: State of Connecticut.; Official web site of the Connecticut Office of the Child Advocate.

core   +1 more source

Child Welfare Services’ Assessments of the Best Interests of the Child from an Ethical Perspective

Social Sciences
This article adopts an ethical perspective on child welfare practice. Drawing on interviews with parents whose children have been taken into care from the project “Care Orders from a Parental Perspective”, we show how an ethical lens offers alternative ...
Hilde A. Aamodt, Alicja Olkowska
doaj   +1 more source