Results 61 to 70 of about 1,202,414 (303)

Deconstructing and Reconstructing Rights for Immigrant Children [PDF]

open access: yes, 2014
Children rights advocates and scholars alike continue to call for the development of innovative and alternative rights models, which specifically provide for an expansive conceptualization of children’s rights.
Corcoran, Erin B.
core   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Realising the Child's Best Interests: Lessons from the Child Justice Act to Improve the South African Schools Act

open access: yesPotchefstroom Electronic Law Journal, 2016
Although the contexts of school discipline and child justice differ considerably there are a number of contact points and points that overlap. Since the South African Schools Act 84 of 1996 came into operation in 1996, the Constitutional Court has made ...
Mariëtte Reyneke
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

The right to live in a family and the subsidiarity of adoption in the light of the best interests of the childs

open access: yesRevista Facultad de Jurisprudencia, 2019
Adoption rates in Chile, in relation to the number of children placed in alternative care systems, are considerably low. Although there are a multiplicity of factors that motivate the previous situation, one that we consider of particular relevance, is ...
Alejandra Illanes Valdés
doaj  

Three perspectives on the notion of ‘the best interests of the child’

open access: yesIn die Skriflig
The research reported in this article was centred on three research questions about the issue of ensuring that, in education and schooling, the principle of the best interests of the child is respected.
Johannes L. Van der Walt   +1 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

"For the Sake of the Children": South African Family Relocation Disputes [PDF]

open access: yesPotchefstroom Electronic Law Journal, 2011
Decisions by primary caregiving parents to relocate after divorce, thereby disrupting the non-primary caregivers’ right of contact with children or, where both parents have joint care, the denial of the other’s parental rights and responsibilities to ...
W Domingo
doaj  

Best Interest of the Child

open access: yesPolis, 2019
In this paper we aim to discuss the best interest of the child as one of the one of the key principles and priorities to international and domestic law. The purpose of this study is to treat the legal aspect for best interest of the child especially related to adoption institute and on the possibility of children’s adoption by homosexuals ...
openaire   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

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