Results 91 to 100 of about 190,253 (294)

Evolution of Prime Editing: Enhancing Efficiency and Expanding Capacity

open access: yesAdvanced Science, EarlyView.
Most rare diseases are caused by genetic mutations. Prime editing (PE) has emerged as a versatile tool capable of inducing diverse mutations without generating DNA double‐strand breaks. Despite its significant clinical potential, PE faces limitations in terms of efficiency and scalability.
Jihyeon Yu   +5 more
wiley   +1 more source

A Scalable Framework for Comprehensive Typing of Polymorphic Immune Genes from Long‐Read Data

open access: yesAdvanced Science, EarlyView.
SpecImmune introduces a unified computational framework optimized for long‐read sequencing to resolve over 400 highly polymorphic immune genes. This scalable approach achieves high‐resolution typing, enabling the discovery of cross‐family co‐evolutionary networks and population‐specific diversity.
Shuai Wang   +5 more
wiley   +1 more source

Induced Ranked Set Sampling when Units are Inducted from Several Populations

open access: yesStatistica, 2018
The method of ranked set sampling when units are to be inducted from several bivariate populations is introduced in this work. The best linear unbiased estimation of a common parameter of two bivariate Pareto distributions is discussed based on the n ...
P. Yageen Thomas, Anne Philip
doaj   +1 more source

The Equality Between Linear Transforms of Ordinary Least Squares and Best Linear Unbiased Estimator [PDF]

open access: yes, 1998
The best linear unbiased estimator BLUE (CXb) of a linear transform CX b in the general Gauss-Markov model (y, E (y) = X b Cov (y) =a2v) is the linear transform C BLUE (Xb) of the best linear unbiased estimator BLUE (Xb) of Xb. Similarly, for the ordinary least squares estimator OLSE (CXb) = C OLSE (X) .
Groß, Jürgen, Trenkler, Götz
openaire   +3 more sources

In‐Operando 4D‐STEM and STEM‐EBIC Imaging of Electric Fields and Charge Carrier Behavior in Biased Silicon p–n Junctions

open access: yesAdvanced Electronic Materials, EarlyView.
This work presents a study of how 4D‐STEM centre of mass measurements and STEM‐EBIC can be used to map the positions, directions, and strengths of electric fields in semiconductor devices. The contrast mechanisms of both techniques are tested and compared with simulations to build a robust analysis of an in situ device in the electron microscope ...
Eoin Moynihan   +5 more
wiley   +1 more source

Best Linear Unbiased Estimate from Privatized Contingency Tables

open access: yes
In differential privacy (DP) mechanisms, it can be beneficial to release "redundant" outputs, where some quantities can be estimated in multiple ways by combining different privatized values. Indeed, the DP 2020 Decennial Census products published by the U.S. Census Bureau consist of such redundant noisy counts.
Awan, Jordan   +3 more
openaire   +2 more sources

Do outgrower schemes enhance technology adoption and productivity? Evidence from maize farmers in Northern Ghana

open access: yesAgribusiness, EarlyView.
Abstract Nucleus outgrower schemes are contractual arrangements where well‐resourced large‐scale farmers (nucleus farmers) are empowered by development support agencies to take charge of smallholder farmers, by providing them with market access and the necessary training on agronomic practices and farm inputs for production.
Dominic Tasila Konja, Awudu Abdulai
wiley   +1 more source

"Prediction in Multivariate Mixed Linear Models" [PDF]

open access: yes
The multivariate mixed linear model or multivariate components of variance model with equal replications is considered.The paper addresses the problem of predicting the sum of the regression mean and the random e ects.When the feasible best linear ...
M. S. Srivastava, Tatsuka Kubokawa
core  

Analyzing individual rent price ratios in eastern German agricultural land markets: A GAMLSS approach

open access: yesAgribusiness, EarlyView.
Abstract This study explores the rent price ratio in agricultural land markets, crucial for evaluating market efficiency, policy needs, and farmer decision‐making. Traditionally, the analyses faced challenges due to the absence of concurrent sale and rent data for the same land, potentially leading to biased results.
Marius Michels   +4 more
wiley   +1 more source

Out of Sample Estimation for Small Areas using Area Level Data

open access: yes, 2005
A Fay-Herriot type model with independent area effects is often assumed when small area estimates based on area level data are required. However, under this approach out of sample areas are limited to synthetic estimates.
Chambers, Ray, Saei, Ayoub
core  

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