Results 131 to 140 of about 7,836,569 (290)

Harnessing machine learning and optimization for informed chemical engineering decisions: A styrene reactor analysis

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
This study shows that integrating multiple machine learning models with optimization and decision‐making improves chemical process design, and that a consensus‐based strategy across models provides more robust and reliable operating recommendations than any single model, especially under limited or noisy data conditions.
Farough Agin   +2 more
wiley   +1 more source

Dynamic survival risk prediction with time‐varying high‐dimensional images

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract Integrating longitudinal data with survival models is a prevalent strategy for dynamic survival risk prediction while accounting for subjects' longitudinally observed variables. However, existing methods primarily focus on scalar longitudinal data and seldom tackle the complexities associated with high‐dimensional longitudinal imaging data ...
Bingfan Liu   +7 more
wiley   +1 more source

The life and work of Ernest Sydney Keeping

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract This article reviews the life and contributions of Ernest S. Keeping (1895–1984), a British‐born physicist who became a mathematics professor at the University of Alberta in 1929. He played a pivotal role in shaping the university's Mathematics Department, serving as its head from 1954 to 1961, and continuing to teach until 1970, nine years ...
David R. Bellhouse, Christian Genest
wiley   +1 more source

Irregular visits in longitudinal studies: Comparing inverse intensity of visit weighting and imputation in a causal analysis of antidepressant therapeutic treatment

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract Irregular observation times are common in longitudinal observational studies and can affect causal inferences. We use data from electronic health records of Kaiser Permanente Washington patients in the United States who initiated an antidepressant medication between 2008 and 2018, with a confirming diagnosis of depression. We are interested in
Janie Coulombe   +2 more
wiley   +1 more source

Some equivalences in linear estimation (in Russian) [PDF]

open access: yes
Under normality, the Bayesian estimation problem, the best linear unbiased estimation problem, and the restricted least-squares problem are all equivalent.
Dmitry Danilov, Jan R. Magnus
core  

Risk of Bias Associated with Varying Sampling Strategies for External Comparator Cohorts for Single‐Arm Trials: Insights from Aggressive Lymphoma

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Marketing authorizations for oncology drugs are often based on single‐arm trials (SATs), and real‐world data‐based external comparator cohorts (ECCs) are increasingly explored to contextualize results. In retrospective studies, comparators may be identified by time of diagnosis but included based on time of relapse; such sampling strategies can ...
Mikkel Runason Simonsen   +6 more
wiley   +1 more source

"Prediction in Multivariate Mixed Linear Models" [PDF]

open access: yes
The multivariate mixed linear model or multivariate components of variance model with equal replications is considered.The paper addresses the problem of predicting the sum of the regression mean and the random e ects.When the feasible best linear ...
Tatsuka Kubokawa, M. S. Srivastava
core  

Enhancing Evidence Generation by Linking Randomized Clinical Trials to Real‐World Data: The INVESTED‐Medicare Linkage Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Real‐world evidence (RWE) derived from real‐world data (RWD) can complement randomized controlled trials (RCTs), yet the validity of RWD relative to RCT data remains insufficiently characterized. We obtained post hoc consent and linked individual participant data from the US‐based INVESTED trial (2016–2019) with Medicare fee‐for‐service claims (2012 ...
Hanseul Cho   +12 more
wiley   +1 more source

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