Results 101 to 110 of about 88,700 (323)

Towards optimal extraction of cosmological information from nonlinear data

open access: yes, 2017
One of the main unsolved problems of cosmology is how to maximize the extraction of information from nonlinear data. If the data are nonlinear the usual approach is to employ a sequence of statistics (N-point statistics, counting statistics of clusters ...
Aslanyan, Grigor   +3 more
core   +1 more source

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang   +18 more
wiley   +1 more source

Estimating parameters of fluctuations in the cosmic microwave background [PDF]

open access: yes, 1995
We address questions that arise in statistical analyses of recently detected fluctuations in the Cosmic Microwave Background (CMB). Estimators of the quadrupole amplitude, Q, and spectral index, n, of the CMB angular fluctuation power spectrum are ...
Lineweaver, Charles H.   +2 more
core   +1 more source

Chromatin Topology Reconfiguration Orchestrates Thermotolerant Male Fertility via GhAL5 in Cotton

open access: yesAdvanced Science, EarlyView.
This study investigates cotton’s high‐temperature (HT) response using multi‑omics. Dynamic 3D genome changes drive expression bias affecting male fertility. The tolerant line shows controlled chromatin dynamics, while the sensitive line exhibits overactivation.
Yanlong Li   +15 more
wiley   +1 more source

Systematic bias of selected estimates applied in vertical displacement analysis

open access: yesJournal of Geodetic Science, 2020
In surveying problems we almost always use unbiased estimators; however, even unbiased estimator might yield biased assessments, which is due to data.
Wyszkowska P., Duchnowski R.
doaj   +1 more source

A Hydrodynamic Bioreactor for High‐Yield Production of Extracellular Vesicles from Stem Cell Spheroids with Defined Cargo Profiling

open access: yesAdvanced Science, EarlyView.
This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir   +7 more
wiley   +1 more source

A Spatial Unit Level Model for Small Area Estimation

open access: yesRevstat Statistical Journal, 2011
This paper approaches the problem of small area estimation in the framework of spatially correlated data. We propose a class of estimators allowing the integration of sample information of a spatial nature.
Pedro S. Coelho , Luís N. Pereira
doaj   +1 more source

Red Blood Cells Internalize Extracellular DNA via Apoptotic Bodies with Clinical Relevance to Cancer Patients

open access: yesAdvanced Science, EarlyView.
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng   +20 more
wiley   +1 more source

Parameter estimation in the Farlie–Gumbel–Morgenstern bivariate Bilal distribution via multistage ranked set sampling

open access: yesAIMS Mathematics
Ranked set sampling is a well-known and efficient method compared to simple random sampling for estimating population parameters. In this study, we focus on the challenge of estimating the scale parameter of the primary variable $ Z $ using a multistage ...
S. P. Arun   +4 more
doaj   +1 more source

Doppler Frequency Shift Based Source Localization in Presence of Sensor Location Errors

open access: yesIEEE Access, 2018
In this paper, the Doppler frequency shift-based localization problem in the presence of sensor location errors is addressed. Based on the measurement model, we present two methods, an explicit solution and a semidefinite relaxation (SDR) technique, to ...
Lijuan Deng   +3 more
doaj   +1 more source

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