Results 181 to 190 of about 7,710 (298)

The difficult discussion on the deactivation of implantable cardioverter devices at the end of life: a systematic review

ESC Heart Failure, Volume 12, Issue 2, Page 733-760, April 2025.
Abstract Implantable cardioverter defibrillators (ICDs) reliably prevent death due to life‐threatening arrhythmias; this may become less relevant in people with more severe heart failure who are reaching the end of life (EOL). This review aimed to explore the ICD deactivation process and identify ethical issues, especially around the initiation of ...
Siobhan C. Murray, Claire McNamara, Anna V. Chatzi   +2 more
wiley   +1 more source

Cell-mechanical parameter estimation from 1D cell trajectories using simulation-based inference. [PDF]

PLoS One
Heyn JCJ, Atienza Juanatey M, Falcke M, Rädler JO.   +3 more
europepmc   +1 more source

Atrial fibrillation development in the heart failure population from nationwide British linked electronic health records

ESC Heart Failure, EarlyView.
Abstract Aims Atrial fibrillation (AF) is a frequent comorbidity in heart failure (HF). We analysed factors associated with new‐onset atrial fibrillation in patients with heart failure using linked real‐world UK data from primary and secondary care, along with findings from genome‐wide association studies. Methods and results Among 163 174 participants
Hiroyuki Yoshimura, Nikhil Paliwal, Arturo Gonzalez‐Izquierdo, Chris Finan, Amand Floriaan Schmidt, Gregory Y.H. Lip, Rui Providencia   +6 more
wiley   +1 more source

Investigation of sample handling steps for accurate heparan sulphate disaccharide analysis using HPLC–MS

ELECTROPHORESIS, EarlyView.
Abstract Heparan sulphates (HSs), a specific class of glycosaminoglycans (GAGs), are important participants of cellular signalling. Analytical characterization of GAGs requires a complex sample preparation workflow. Although a detailed stability and recovery study is available for the chondroitin sulphate GAG class, the literature concerning HS is ...
Domonkos Pál, Gábor Tóth, Lilla Turiák   +2 more
wiley   +1 more source

Robust propensity score estimation via loss function calibration. [PDF]

Stat Methods Med Res
Shang Y, Chiu YH, Kong L.
europepmc   +1 more source

A Practical Approach to Implementing ICH Q14: Tools for Analytical Quality by Design in Capillary Electrophoresis Method Development

ELECTROPHORESIS, EarlyView.
ABSTRACT The ICH Q14 guideline introduces a structured framework for analytical method development based on Analytical Quality by Design (AQbD) principles, aiming to ensure robust, reliable, and fit‐for‐purpose methods throughout the product lifecycle.
Ewoud van Tricht, Cari E. Sänger ‐ van de Griend   +1 more
wiley   +1 more source

James-Stein Estimator Improves Accuracy and Sample Efficiency in Human Kinematic and Metabolic Data. [PDF]

Ann Biomed Eng
Alwan A, Srinivasan M.
europepmc   +1 more source

Effect of stereo‐EEG versus subdural EEG on functional and seizure outcome in pediatric and adult epilepsy surgery: A 21‐year single‐center experience

Epileptic Disorders, EarlyView.
Abstract Objective (1) To compare use, benefits, and complications of stereo‐EEG (SEEG) and subdural EEG (SD) in presurgical epilepsy candidates. (2) To evaluate the effectiveness of both methods in delineation of the epileptogenic zone (EZ) and guiding tailored resective surgery. Methods We included patients with SEEG or SD evaluations in children and
Ahmed Gaballa, Christian G. Bien, Philip Grewe, Anne Hagemann, Thilo Kalbhenn, Tilman Polster, Friedrich G. Woermann, Thomas Cloppenborg   +7 more
wiley   +1 more source

Correlated systematic uncertainties and errors-on-errors in measurement combinations with an application to the 7-8 TeV ATLAS-CMS top quark mass combination. [PDF]

Eur Phys J C Part Fields
Canonero E, Cowan G.
europepmc   +1 more source

Applying the Estimands Framework to Non-Inferiority Trials: Guidance on Choice of Hypothetical Estimands for Non-Adherence and Comparison of Estimation Methods. [PDF]

Stat Med
Morgan KE, White IR, Leyrat C, Stanworth S, Kahan BC.   +4 more
europepmc   +1 more source