Results 111 to 120 of about 800,688 (313)

Experiences and Challenges in Best Practices: Sensors

open access: yes, 2017
Presentation at 'Evolving and Sustaining Ocean Best Practices Workshop, Intergovernmental Oceanographic Commission, Paris, France, 15-17 Nov 2017 ...
Walsh, Ian
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Best Practices Guide Contents

open access: yes, 2014
intellectual property laws.
Best Practices Guide
core  

Quality and completeness of, and spin in reporting of, pilot and feasibility studies in hip and knee arthroplasty: a protocol for a methodological survey

open access: yesBMJ Open
Introduction Pilot or feasibility trials examine the feasibility, viability and recruitment potential of larger, main trials. Specifically, a pilot trial can be instrumental in identifying methodological issues essential to the development of an ...
Lehana Thabane   +4 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Bridging the gap: implementing research results : Michigan Department of Transportation peer exchange report : December 7-9, 2010. [PDF]

open access: yes
The Michigan Department of Transportation (MDOT) Office of Research and Best Practices(ORBP) hosted a peer exchange December 7-9, 2010 in Lansing, Michigan.
Michigan. Dept. of Transportation. Office of Research and Best Practices
core  

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Creating healthy states : promoting healthy living in the Medicaid program [PDF]

open access: yes
Caption title.Also available via the World Wide Web.System requirements: Adobe Acrobat ...

core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Community Experiences and Challenges in Best Practices.

open access: yes, 2018
Presentation at 'Evolving and Sustaining Ocean Best Practices Workshop II, Intergovernmental Oceanographic Commission, Paris, France, 04-06 Dec 2018 ...
Karstensen, Johannes
core  

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