Results 81 to 90 of about 800,688 (313)

Quality Assurance of Oceanographic Observations: Standards and Guidance Adopted by an International Partnership

Frontiers in Marine Science, 2019
Scientists who observe and distribute oceanographic data require a process to ensure high-quality data. This process includes quality assurance, quality control, quality assessment, standards, and best practices.
Mark Bushnell, Christoph Waldmann, Steffen Seitz, Earle Buckley, Mario Tamburri, Juliet Hermes, Emma Henslop, Ana Lara-Lopez   +7 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Best of practices?

, 2007
In this brief critique of the idea of 'best practice', the author argues that good practice is not replicable or uniform; it cannot be reduced to its component parts for replication elsewhere. Furthermore, the criteria for what constitutes 'best practice'
Feek, Warren
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Ocean Best Practices Workshop Introduction.

, 2018
Presentation at 'Evolving and Sustaining Ocean Best Practices Workshop II, Intergovernmental Oceanographic Commission, Paris, France, 04-06 Dec 2018 ...
Pearlman, Jay
core  

Cochrane Africa: a network of evidence-informed health-care decision making across sub-saharan Africa

The Pan African Medical Journal, 2018
Cochrane Africa is a network of researchers and health stakeholders who aim to support the use of high quality Cochrane evidence to improve health outcomes in Africa.
Lawrence Mbuagbaw, Pierre Ongolo Zogo, Tamara Kredo, Solange Durao, Taryn Young, Emmanuel Effa, Martin Meremikwu, Ameer Hohlfeld, Charles Wiysonge   +8 more
doaj   +1 more source

Through the eyes of the student: Best practices in clinical facilitation

Curationis, 2017
Background: Clinical facilitation is an essential part of the undergraduate nursing curriculum. A number of studies address the issue of clinical facilitation in South Africa, but there remains a lack of knowledge and understanding regarding what ...
Immaculate S. Muthathi, Catherine H. Thurling, Susan J. Armstrong   +2 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Best Practices: Documentation, Publishing, Promotion

, 2018
Presentation at 'Evolving and Sustaining Ocean Best Practices Workshop, Intergovernmental Oceanographic Commission, Paris, France, 15-17 Nov 2017 ...
Simpson, Pauline
core  

Guide to agricultural pm10 best management practices [PDF]

, 2008
: The intent of this guide is to: • Provide agricultural operators with information and guidance on how to effectively implement individual best management practices.

core