Results 241 to 250 of about 8,286,670 (284)

Dual-graph attention autoencoder for spatial domain identification in ischemic stroke. [PDF]

Front Neurosci
Chen YY, Hu WT, Zhang G, Rao XL, Jiang T.   +4 more
europepmc   +1 more source

Targeting the PHB2–ACSL3 Lipid‐Remodeling Axis Overcomes Cisplatin Resistance by Restoring Ferroptosis in Gastric Cancer

Advanced Science, EarlyView.
ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu, Wanying Xiang, Xinyue Wang, Yue Pan, Jing Gao, Jiezhen Yang, Yufei Wang, Zhipu Zhu, Man Tong, Lei Jin, Yan Ye   +10 more
wiley   +1 more source

Spatial immune biomarkers in triple-negative breast cancer: emerging evidence, technology trade-offs, and barriers to clinical translation. [PDF]

Front Immunol
Zeng L, Lin W, Xue S, Chen M, Wu H.
europepmc   +1 more source

A Reconfigurable Memristive Spiking Neuron Enabling Advanced Neuromorphic Computing

Advanced Science, EarlyView.
Pek Jun Tiw and co‐workers develop a reconfigurable memristive neuron that can exhibit four spiking behaviors with freely tunable spike train parameters. The neuron supports multiplexed spike encoding of multiple pieces of information. It also supports advanced neural network strategies, such as neural heterogeneity and dynamic mode switching ...
Pek Jun Tiw, Yuqi Li, Zhongyuan Li, Qihang Ding, Yuzhe Wang, Jiarong Wang, Yuchao Yang   +6 more
wiley   +1 more source

Trauma stabilization points in armed conflict: operational evolution and strategic reflections from mosul to Gaza. [PDF]

Eur J Trauma Emerg Surg
Marta C, Luca P, Kai-Hsun H, Areej AF, Athanasios G, Wessam EG, Jonas Z, Johan VS, Luca R, Flavio S.   +9 more
europepmc   +1 more source

GSTM4 Suppresses Prostate Cancer Progression by Targeting TRIM27‐mediated ACLY Ubiquitination and Lipid Metabolism

Advanced Science, EarlyView.
GSTM4 enhances the interaction between ACLY and the E3 ubiquitin ligase TRIM27, thereby increasing K48‐linked ubiquitination at the K554 site of ACLY and promoting its degradation. Consequently, GSTM4 regulates lipid synthesis, as well as the proliferation and metastasis of PCa cells, by modulating ACLY stability.
Kang‐Ping Xiong, Fei Liu, Wang Wang, Gang Wang, Kai‐Yu Qian, Sheng Tu, Si‐Ming Chen, Hui‐Min Xu, Shan‐Shan Zhang, Yong Li, Xing‐Huan Wang, Hong Weng   +11 more
wiley   +1 more source

Spatial and telehealth accessibility to eating disorder treatment in the United States: evidence from registry and LLM-augmented data. [PDF]

Int J Health Geogr
Liu L, Huo C, Beccia AL, Richmond TK, Austin SB.   +4 more
europepmc   +1 more source

SegFormer with Hausdorff distance-based spatial bias and conceptual split gate for automated segmentation of cervical precancerous lesions. [PDF]

MethodsX
Sofiani IR, Suyono H, Yudaningtyas E, Utaminingrum F.   +3 more
europepmc   +1 more source