Results 101 to 110 of about 13,466,899 (339)

Response to “Environmental scan and evaluation of best practices for online systematic review resources”

open access: yesJournal of the Medical Library Association, 2018
Comment on Parker RMN, Boulos L, Visintini S, Ritchie K, Hayden J. Environmental scan and evaluation of best practices for online systematic review resources. J Med Libr Assoc. 2018 Apr;106(2):208–17. DOI: http://dx.doi.org/10.5195/jmla.2018.241.
Chris Champion
doaj   +1 more source

The Best Test of Ph.D. Student Success—Response

open access: yesScience, 2010
Newquist suggests that students' publications are important predictors of post-degree research effectiveness, due in part to the importance of collaboration in innovative research. We agree that publication record is important and helpful, but the collaborative aspects of writing render ...
Feldon, David F.   +2 more
openaire   +3 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

TREX1, a predator for treating MSI‐H tumors?

open access: yesMolecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya   +2 more
wiley   +1 more source

Places of Refuge for Ships in Need of Assistance. Looking for the Best Response

open access: yesPaix et Sécurité Internationales, 2017
The oil spills, as a result of accidents involving tankers combined with the ambiguities that affect this area of international law, have shed light on the need to take steps aimed at providing places of refuge for ships in need of assistance.
Belén Sánchez Ramos
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

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