Results 41 to 50 of about 6,428,588 (298)

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Immune checkpoint inhibitor (ICI)-based treatment beyond progression with prior immunotherapy in patients with driver-gene negative advanced non-small cell lung cancer

BMC Cancer
Background No definite conclusion has yet to be reached for immunotherapy beyond progression(IBP) of first-line immunotherapy as the second-line treatment for advanced NSCLC patients with negative driver genes.
Min Wang, Xuquan Jing, Feihu Chen, Shuangqing Lu, Yulan Sun   +4 more
doaj   +1 more source

Best Practices in Peer Assessment: Training Tomorrow’s Physicians to Obtain and Provide Quality Feedback [Response to Letter]

Advances in Medical Education and Practice, 2020
Sarah Lerchenfeldt, Tracey AH Taylor Department of Foundational Medical Studies, Oakland University William Beaumont School of Medicine, Rochester, MI, USACorrespondence: Tracey AH TaylorOakland University William Beaumont School of Medicine, O&rsquo ...
Lerchenfeldt S, Taylor TAH
doaj  

Chemosensory deficits are best predictor of serologic response among individuals infected with SARS-CoV-2.

PLoS ONE, 2022
ObjectiveSmell and taste alteration are closely linked to infection with SARS-CoV-2 and may be associated with a more indolent disease course. Serologic response rates among individuals with mild disease remains limited.
Jonathan B Overdevest, Alexandria L Irace, Valeria Mazzanti, Eun Jeong Oh, Paule V Joseph, Davangere P Devanand, Zachary C Bitan, Eldad A Hod, David A Gudis, Codruta Chiuzan   +9 more
doaj   +1 more source

The Best Under Stress: An Analysis of Breast Tissue Expander Response to External Forces

Aesthetic Surgery Journal Open Forum, 2023
BackgroundThe use of breast tissue expanders (TEs) in breast reconstruction is accompanied by undesired changes to the chest wall and lateral plane.
Daniel Najafali, Farrah C Liu, Karanvir Raman, Bhagvat Maheta, Golddy Milagros Saldana, Lucas Heldman, Priscila Cevallos, Rahim Nazerali   +7 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

PROPOSED CRITERIA TO SELECT BEST AVAILABLE TECHNIQUES (BATS) FOR OIL SPILL RESPONSE

Chemical Engineering Transactions, 2009
Not available.
G. Guidi, F. Gugliermetti, A.C. Violante
doaj   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Hyperandrogenism and menstrual imbalance are the best predictors of metformin response in PCOS patients

Reproductive Biology and Endocrinology, 2022
Background Moving from the correlation between insulin-resistance and PCOS, metformin has been administered in some PCOS women improving ovulatory and metabolic functions and decreasing androgen levels.
Emanuele Garzia, Valentina Galiano, Giovanni Marfia, Stefania Navone, Enzo Grossi, Anna Maria Marconi   +5 more
doaj   +1 more source