Results 71 to 80 of about 6,428,588 (298)
BMC Medical Research MethodologyBackground The timing of treating cancer patients is an essential factor in the efficacy of treatment. So, patients who will not respond to current therapy should receive a different treatment as early as possible. Machine learning models can be built to
Elham Majd, Li Xing, Xuekui Zhang
doaj +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga +8 more
wiley +1 more source
On the Convergence Time of the Best Response Dynamics in Player-specific Congestion Games
, 2008 We study the convergence time of the best response dynamics in player-specific singleton congestion games. It is well known that this dynamics can cycle, although from every state a short sequence of best responses to a Nash equilibrium exists. Thus, the
Ackermann, Heiner, Roeglin, Heiko
core
Nash equilibria sets in mixed extended 2x3 games [PDF]
Computer Science Journal of Moldova, 2005 We describe the Nash equilibria set as an intersection of best response graphs. The problem of Nash equilibria set construction for \hbox{two-person} mixed extended 2x3 games is studied.
Valeriu Ungureanu, Ana Botnari
doaj
Molecular Oncology, EarlyView.We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin +10 more
wiley +1 more source
A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer
Molecular Oncology, EarlyView.Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla +15 more
wiley +1 more source
Trust Exploitation and Attention Competition: A Game Theoretical Model
, 2016 The proliferation of Social Network Sites (SNSs) has greatly reformed the way of information dissemination, but also provided a new venue for hosts with impure motivations to disseminate malicious information.
Fu, Hao +4 more
core +1 more source
Partition of the genetic trend to validate multiple selection decisions
Animal, 2008 In this note, a procedure to partition the genetic trend of a selected population is presented. Each part of the genetic gain accounts for the Mendelian sampling terms of different groups of animals, which can be sometimes assigned to different selection
L.A. García-Cortés +2 more
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Physiological Reports, 2020 It is crucial for animals to discriminate between palatable (safe) and aversive (toxic) tastants. The mechanisms underlying neuronal discrimination of taste stimuli remain unclear.
Tatsuko Yokota +4 more
doaj +1 more source