Results 81 to 90 of about 13,466,899 (339)

The Best Response Paradigm: A New Approach to Test Implicatures of Complex Sentences

Frontiers in Communication, 2018
There is a controversial debate about which implicatures are triggered by logically complex sentences. This article introduces a novel experimental paradigm based on a game-theoretic design to test these implicatures.
Nicole Gotzner, Anton Benz
doaj   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Oncology practice during COVID-19 pandemic: a fast response is the best response [PDF]

, 2020
Cinthya Sternberg, Thamine Lessa Andrade, Ana Paula Gomes Alcântara Villa Nova, Bianca Vivas Fiscina, Ana Paula Laranjeira Fernandes, Camila Alves, Adriana Batista Alves, Lise Hizumi, Simone Sacramento Novais Dias, Pablicio Nobre, Aknar Calabrich, Anelisa K. Coutinho, Alex Pimenta da Silva   +12 more
openalex   +1 more source

The Lottery Contest is a Best-Response Potential Game

, 2017
It is shown that the n-player lottery contest admits a best-response potential (Voorneveld, 2000). This is true also when the contest technology reflects the possibility of a draw.
Christian Ewerhart
semanticscholar   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

The gut microbiota as a potential biomarker in patients with EGFR-mutant lung cancer

Scientific Reports
Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) are highly effective against EGFR-mutant non-small cell lung cancer (NSCLC); however, identifying biomarkers that predict prognosis and adverse events is necessary.
Chiori Tabe, Daisuke Motooka, Toshitsugu Fujita, Tomonori Makiguchi, Kageaki Taima, Hisashi Tanaka, Masamichi Itoga, Yoshiko Ishioka, Takahiro Akita, Mina Ishidoya, Kei Chubachi, Takashi Fukushima, Yusuke Tanaka, Haruka Odagiri, Yuko Kameyama, Yuri Kobori, Sadatomo Tasaka, Hodaka Fujii   +17 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Segmentation of patients with small cell lung cancer into responders and non-responders using the optimal cross-validation technique

BMC Medical Research Methodology
Background The timing of treating cancer patients is an essential factor in the efficacy of treatment. So, patients who will not respond to current therapy should receive a different treatment as early as possible. Machine learning models can be built to
Elham Majd, Li Xing, Xuekui Zhang
doaj   +1 more source

The Efficiency of Best-Response Dynamics [PDF]

, 2020
Michal Feldman, Yuval Snappir, Tami Tamir   +2 more
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source