Results 71 to 80 of about 245,414 (303)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
I-BET-762 treatment suppresses lung inflammatory cytokines after IFNγ/LPS stimulation.
, 2016 Effect of I-BET-762 administration on MCP-1, KC, TNFα, IL-27p28 and IFNγ (A) mRNA levels and (B) protein levels in whole lung tissue. Representative of three independent experiments, n = 6–8 mice per group, presented as mean ± SEM.
Ming Yang (109148) +4 more
core +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
I-BET-762 treatment suppresses AHR and inflammatory cells after IFNγ/LPS stimulation.
, 2016 Mice were administered IFNγ/LPS i.t at 0h. Some mice were treated with I-BET-762 or vehicle (hydroxyl-β cyclodextrin) i.v 1h before and 4h after IFNγ/LPS exposure. Endpoints were assessed at 12h.
Ming Yang (109148) +4 more
core +1 more source
Orbital: The Electronic Journal of Chemistry, 2017 This study reports the production of activated carbon (AC) from chemical activation with sodium hydroxide in pyrolysis temperature of 500 to 600 °C using alternative and renewable material, Buriti petiole.
Cristiane Freitas de Almeida +6 more
doaj +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Recombinant MCP-1 administration overcomes I-BET-762-mediated suppression of AHR and inflammation.
, 2016 Mice were administered IFNγ/LPS/rMCP-1 i.t at 0h. Some groups were treated with I-BET-762 i.v 1h before and 4h after IFNγ/LPS/rMCP-1 exposure. Endpoints were assessed at 12h.
Ming Yang (109148) +4 more
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
, 2016 Pulmonary macrophages were isolated from naïve mice and stimulated with IFNγ/LPS in presence of I-BET-762 or vehicle for 12h. Expression of MCP-1 (A), KC (B), TNFα (C), IL27p28 (D), and IFNγ (E) were assessed by qPCR. Values are presented as mean ± SEM. *
Ming Yang (109148) +4 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source